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Opening the AI ‘black box’ for glaucoma

3 February 2026 | | EYE - Glaucoma
Artificial intelligence (AI) models show great promise for glaucoma detection using retinal images, but their ‘black box’ nature is a major barrier to clinical adoption. Clinicians are often hesitant to trust a diagnosis without understanding its reasoning. This paper provides...
Ophthalmology journal front cover image.

Low-dose bimatoprost/timolol gel: a new fixed-combination option

3 February 2026 | | EYE - Glaucoma
This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...

From dry eyes to glaucoma: How the menopause impacts your eyes and what to do about it, according to an optician

25 October 2024 | menopause, dry eye, eye drops, Nimmi Mistry, WMD2024, cornea, glaucoma, cataracts, oestrogen, Vision Direct, opticians, optometry
Menopause, much like entering puberty, comes with hormonal disruptions that change a woman's body and behaviour. Some of the first visible side effects are hot flushes, weight gain, and acne, accompanied by behavioural symptoms like mood swings, insomnia, and brain...

Doctor prints cornea on demand!

1 April 2019 | | EYE - Cornea, EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Doctor prints cornea on demand! Dr Hideo Kodama from the Nagoya Municipal Industrial Research Institute first...

A curry a day could keep the ophthalmologist away

2 December 2019 | | EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: A curry a day could keep the ophthalmologist away The dietary supplement market is a multibillion-dollar...

Breakthroughs in the genetics of angle-closure glaucoma

1 April 2017 | | EYE - Glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Management of diabetic macular oedema in vitrectomised eyes

1 August 2016 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is one of the leading causes of blindness; its prevalence is on the rise with progressive increase in numbers of people suffering from diabetes. The management of DMO has evolved significantly over the past few years....

Usher syndrome: an overview

22 September 2020 | | EYE - Vitreo-Retinal, EYE - General
Usher syndrome is the most common hereditary condition that affects both vision and hearing. It is an autosomal recessive condition characterised by retinitis pigmentosa (RP) and bilateral sensorineural hearing loss [1,2]. Usher syndrome is the cause of approximately 10% of...

Randomisation, confounding & observational methods in ophthalmic epidemiology

1 June 2022 | | EYE - General
Randomisation and confounding Understanding the relationship between an exposure and an outcome of interest is the central challenge in ophthalmic epidemiology. The exposure may be aetiological, taking the form of a putative risk biological factor, or therapeutic, in the form...

Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?

12 February 2025 | | EYE - Pathology, EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...

Developments in retinal pigmentation measurement and the hopes of an equitable future

4 August 2025 | | EYE - Vitreo-Retinal, EYE - Imaging
Our AI & Oculomics co-editor, Nima Ghadiri, sat down with Abraham Olvera-Barrios from Moorfields and Anand Rajesh from the University of Washington to discuss their recent international study into retinal pigmentation and its wider clinical, technological and academic applications. Can...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

1 December 2015 | | EYE - Neuro-ophthalmology
Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...