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IgG4-related disease or Graves orbitopathy

This is retrospective review of patients who had been diagnosed with both IgG4-related ophthalmic disease (IgG4-ROD) and Graves orbitopathy over a four year period. Eight patients were identified. The diagnosis of IgG4-ROD was based on 10 or more IgG4+ plasma...

Brolucizumab in age-related macular degeneration, HAWK Study

The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

Topical insulin for neurotrophic ulcers

This retrospective case series described the use of topical insulin drops as an aid in treatment of refractory neurotrophic corneal ulceration in six patients. Insulin drops were prepared under sterile conditions from standard insulin preparations mixed with artificial tears containing...

Does Acanthamoeba need bacteria to cause keratitis?

An animal study was carried out on 36 rabbits, whose corneas were inoculated with either Acanthamoeba castellanii alone, Pseudomonas aeruginosa alone or both pathogens together after a period of short (two hours) or long (six hours) co-incubation. The clinical severity...

Cytotoxic effect of voriconazole on human corneal epithelial cells

Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...

Review of efficacy and safety of tetracaine drops in strabismus surgery

Tetracaine is a topical anaesthetic drug used to anesthetise the eye and surrounding areas during strabismus surgery. It is generally safe and well tolerated but can cause mild adverse reactions at the site of use and, in rare cases, serious...

Smart speakers: for patients and practitioners

Many readers will have experience of using smart speakers, such as the Amazon Echo or the Google Home. These popular devices are inexpensive and powerful. In brief, smart speakers listen for a spoken trigger word, followed by verbal commands. Commands...

What's trending Apr/May 2023

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Cyborgeye #flashlighteye #prostheticeye #BrianStanleyeye Brian Stanley is a California-based engineer, who lost his eye to retinoblastoma when he was six-years-old. A...

What's trending Aug/Sep 2018

#QueenElizabeth #cataract It is well and truly summer! Queen Elizabeth was spotted in her sunnies during recent events, not just as a fashion accessory, or to shield the hot British summer sun. As it transpires, she underwent successful cataract surgery....