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Inflammation and microvascular changes in diabetic retinopathy

Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...

Germline mutation risk in solitary unilateral retinoblastoma

This study aimed to determine the true risk for germline mutation in a child presenting with solitary unilateral RB and whether this risk differs by age at presentation. This was a retrospective review of 482 cases from 1972-2020. Age groups...

Comparison of treatment regimes for APROP

The authors evaluated the risk factors and treatment outcomes of various treatment options for APROP including intra-vitreal anti-VEGF injections, laser treatment and a combination of both. This was an observational study of all consecutive cases of untreated APROP from 2018-19...

OCT findings after strabismus surgery for macular, choroidal and nerve fibre thickness

This study used OCT to investigate the changes in the central macular thickness, subfoveal choroidal thickness (SFCT) and retinal nerve fibre layer (RNFL) after horizontal rectus surgery for patients with strabismus. This was a retrospective study and patients were grouped...

Comparing bimedial rectus recession and botulinum toxin for partially accommodative esotropia

The authors present a retrospective case review to compare bimedial rectus recession and botulinum toxin injection to the medial recti. This study was possible due to the different first-line preferences of the individual surgeons within the team. Inclusion criteria were...

Dichoptic vs occlusion therapy outcomes for anisometropic amblyopia

The authors evaluated a binocular Tetris game for Android phones and compared its effectiveness, compliance and adverse events with part-time patching in children with anisometropic amblyopia. This was a prospective randomised study. Group 1 played the game for two hours...

Proptosis reduction with teprotumumab versus surgical decompression

This study aims to explore whether fat-to-muscle ratio (FMR) can be used to determine the efficacy of teprotumumab when compared to surgical decompression. Simply put, a high FMR equates to more fat expansion and low FMR equates to more muscle...

Intermittent exotropia and refractive change in children

The authors present a retrospective case review with the aim of examining the relationship between refractive change and intermittent exotropia (IXT). The medical records of patients were reviewed for those aged 18 years old and younger diagnosed with IXT with...

Randomised controlled trial of CAM training vs occlusion for amblyopia therapy

The main aim of this study was to compare the effect of Cambridge vision stimulator (CAM) therapy with passive occlusion in the management of unilateral amblyopia. This was an randomised control trial (RCT) with two groups; group 1 with CAM...

Ocular sequalae of spinal muscular atrophy

The authors present a retrospective single-centre cohort study of patients with spinal muscular atrophy – a neurodegenerative disorder presenting between infancy and early adulthood. Forty-eight patients were included in total, with roughly equal numbers of types 1, 2 and 3...