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MicroRNA inhibits corneal neovascularisation

1 August 2018 | | EYE - Cornea, EYE - General | Biomechanical stress, Corneal epithelium, MicroRNA-204, Neovascularization, VEGF, VEGFR2
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

Enzymatic clearance of anterior chamber infiltrate in uveitis

1 February 2014 | | EYE - Vitreo-Retinal
Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...

Retinal vessel diameter in pseudoexfoliation

5 February 2020 | | EYE - Vitreo-Retinal
Pseudoexfolation (PEX) is characterised by deposition of fibrillary extracellular material on ocular and extraocular tissue. Studies have shown that deposition in vascular structures cause hypoxia and ischaemia. In the eye, a decrease in blood supply to the optic nerve can...

Lagophthalmos as a potential complication of COVID-19

1 February 2022 | | EYE - Neuro-ophthalmology, EYE - General | Bell’s palsy, COVID-19, anosmia, coronavirus, Lagophthalmos
Lagophthalmos is a condition associated with the inability to close the eyelids effectively, with the main cause being facial nerve palsy. The authors aimed to investigate whether lagophthalmos was associated with coronavirus infection (COVID-19) by comparing patients diagnosed with lagophthalmos...

Impact of solar eclipses on vision

4 December 2024 | | EYE - Vitreo-Retinal
Solar retinopathy occurs as a result of mechanical and photochemical damage to the retina caused by exposure to excessive light. The authors presented the optical coherence tomography (OCT) and OCT-angiography findings of five patients who looked at the solar eclipse...

The refractive index in the eye lens – implications for clinical practice and optical design

1 August 2016 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
The eye may appear to be a comparatively simple organ and yet its optical system is complex and continues to be a source of investigation and research. The major optical elements are considered to be the cornea and the lens...

The world in union

4 October 2023 |
"It’s the world in union, the world as one…” Hearing these lyrics as a sports fan means only one thing: it’s time for the Rugby World Cup! This four-yearly sporting extravaganza should hit your TV screens around the same time...

Aqueous misdirection: a case series of unexpected surgical complications

3 June 2024 | | EYE - Glaucoma
Aqueous misdirection (AM), also known as malignant glaucoma, is a form of secondary glaucoma that typically presents with shallowing of the anterior chamber (AC), raised intraocular pressure (IOP), and reduced visual acuity (VA) in the presence of patent peripheral iridotomies...

Ophthalmology Foundation: a promising new beginning

3 June 2021 | | EYE - General
The world’s leaders in ophthalmology have created the new Ophthalmology Foundation, to make prevention of blindness and maintenance of high quality vision accessible to people of all nations. Board of Directors President David EI Pyott explains their vision for the...

The final step

1 April 2017 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Not long after securing my fellowship in London I was successful at interview for a consultant post at Singleton Hospital, Swansea. The interview took place before I had actually started in London and besides the basic things that are asked...

Will it change management?

1 February 2017 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Like most doctors I have read and am a fan of Samuel Shem’s House of God, with my favourite Rule being Rule 10: “If you don’t take a temperature you can’t find a fever.” If you don’t intend to treat...

Lines, dots, spots and rings in ophthalmology: understanding eponyms

1 April 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Eponymous names are familiar to all who have undergone undergraduate and postgraduate training in medicine. The ability to name a few allows one to stand out among your peers and rare, or not so rare, eponymous syndromes are a favourite...