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ROPPVAL Syndrome as a differential diagnosis to optic neuritis

Optic neuritis (ON) is a common cause of visual loss in young patients. Patients with eye pain and ipsilateral visual loss are often referred into neuro-ophthalmology clinics with a possible diagnosis of ON. In 2018 Jefferis et al. reported a...

Outcomes after surgery for INS

The purpose of this study was to detail clinical and electrophysical outcomes after extraocular muscle surgery in adults with infantile nystagmus syndrome (INS). This was a single centre prospective case series of 81 patients aged 18-72 years (mean 36); 63%...

Anatomical variations of the nasolacrimal system

The authors report a retrospective observational case series of 734 dacryocystography images; 689 from adult patients and 45 from paediatric patients. Of these 734 images, 35 (4.8%) were found to have an anatomical variant where the nasolacrimal duct emerged from...

Diagnostic and prognostic roles of serum interleukin-6 in patients with uveitis

This is a retrospective observational case series investigating the diagnostic and prognostic role of serum interleukin (IL)-6 in patients with uveitis involving 80 patients – 60 patients (75%) with normal IL-6 levels and 20 patients (25%) with high IL-6 levels....

Lacrimal drainage system malignancies

This retrospective case series looks at the rare cases of lacrimal drainage system malignancies. The authors have identified 14 patients in 24 years, at a tertiary referral centre in the Indian subcontinent. Many previous publications have found squamous cell carcinoma...

Teprotumumab for chronic TED

This retrospective case series looks at the use of teprotumumab in nine patients with thyroid eye disease (TED) of clinical activity score ≤one and >nine months duration, in an American cohort. Current European guidelines have suggested the use of teprotumumab...

Management options for microphthalmia with orbital cyst with / without visual potential

The authors present six cases (seven eyes) of congenital microphthalmia and orbital cyst. These cases were newborn mainly with one aged 20 years. There were four females and two males and two of seven eyes had a visual potential of...

Hydrogel expanders in the management of congenital anophthalmia

This is a retrospective case series of 11 anophthalmic orbits in eight children. Anophthalmia can result micro-orbitism, congenital fornix atresia, constricted socket, phimotic lids and reduced palpebral aperture. Expanders play an important role in improving the orbital volume and forniceal...

Outcomes from evisceration with primary implant in 1800 patients

This is a retrospective analysis of 1800 patients who had evisceration with orbital implant between 2013-2019. As the largest published series on this topic, the authors are able to give relatable real-world data on complications following surgery. They use a...

Visual acuity outcomes after cataract surgery in type 2 diabetes (NIDDM): the action to control cardiovascular risk in diabetes (ACCORD) study

This is a retrospective case-control study of 1136 eyes enrolled in the 784 ACCORD patients receiving cataract surgery between 2001-2014. 362 / 1136 eyes had gradable fundus photography for diabetic retinopathy (DR). Seven hundred and sixty-two eyes (67.1%) achieved 20...

Scleral perforation after strabismus surgery

The aim of this study was to report the incidence, risk factors, treatment and outcomes of scleral perforation as a vision-threatening complication of strabismus surgery. The review included 12 papers: four prospective, two retrospective, two surveys, one review, two animal...

Hughes flap for lower lid retraction

This is a retrospective case series looking at the use of Hughes flap for cicatricial lower lid retraction. Fourteen patients were identified across five different hospitals with varying aetiologies ranging from previous lid lesion excision and reconstruction to trauma. The...