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Tear production levels and dry eye disease

Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...

Cataract in patients with pseudoexfoliation syndrome

The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...

IgG4 related orbital disease

This retrospective study was done to determine the prevalence of IgG4 related orbital disease (IgG4ROD) in patients who previously had biopsies for suspected idiopathic orbital inflammatory disease (IOID) and / or orbital lymphoproliferative disease (OLD). The charts and slides of...

Histopathological changes in rabbit retinitis pigmentosa

The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...

The impact of conjunctivochalasis on dry eye symptoms and signs

The study aimed to draw a relationship between conjunctivochalasis and dry eye symptoms via a dry eye questionnaire (DEQ5), as well as signs such as tear osmolarity, tear break up time, corneal staining, Schirmer score, meibomian gland dropout, eye lid...

Meibomian gland dropout in patients with dry eyes

In this prospective study 264 patients with symptoms of dry eye were examined with a non-contact meibography system to assess the morphological changes in their meibomian glands. These patients were not previously diagnosed with meibomian gland dysfunction and patients with...

Pterygium ocular surface temperature

This prospective study investigated the ocular surface temperature in patients with pterygia compared to those with dry and healthy eyes respectively. Previous studies have shown that patients with dry eyes show a significant decrease in ocular surface temperature on sustained...

Liquid adhesive bandage for clear corneal cataract incisions

This paper reports a prospective randomised controlled trial of patients undergoing routine phacoemulsification with a 2.75mm clear corneal incision and followed up for 14 days postoperatively. They evaluated wound edge closure, surgically induced astigmatism and foreign body sensation after use...

My top five: Elective grants for an ophthalmology elective for a medical student surviving in a cost-of-living crisis

In a time where cost of living is significantly increasing, and the student NHS bursary is remaining stagnant, funding a medical elective is becoming increasingly more challenging for medical students. Surveys have shown that medical students typically get two to...

Visual consequences of congenital hypothyroidism

This study evaluated the frequencies of ophthalmic abnormalities in Turkish children with a history of congenital hypothyroidism in a retrospective study of 121 children. Median age was nine months (one to 216) at initial ophthalmic examination. Forty children were ex-premature...

Medical Ophthalmological Society Annual Meeting

By Muhammad Adil Seelarbokus, Final Year Medical Student, Newcastle University. With an ever-increasing ageing population with multiple co-morbidities presenting to clinics nowadays, the need for medical ophthalmologists is growing. The Medical Ophthalmological Society’s Annual Meeting seemed to be an excellent...