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Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

1 April 2016 | | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

Ocular manifestations of multiple sclerosis: an overview

1 December 2022 | | Ophthalmology, Genetics
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics

5 April 2022 | | Ophthalmology, Retina / Uvea / Vitreous
The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...

Addressing medical risk factors for diabetes and understanding the new systemic treatments

1 February 2014 |
As global diabetes figures continue to rise, the importance of reducing the burden of macrovascular and microvascular complications of diabetes has never been so great. By 2025 it is estimated that five million people in the UK will have diabetes...

Toxoplasmosis and the associated retinochoroiditis: important facts and when to treat

1 April 2017 | | Retina / Uvea / Vitreous
Annie SeeWah Tung provides an overview of toxoplasmosis retinochoroiditis, including guidance on which cases should be treated and the treatment options. Toxoplasmosis retinochoroiditis is an infectious condition that is characterised by retinochoroidal lesions commonly in the posterior pole and is...

Thermal injury and false eyelashes

1 April 2020 | | Ophthalmology, Optometry, Emergency Ophthalmology
The authors provide a case of cyanoacrylate glue causing a thermal burn on the eyelid and explain how this type of burn should be managed. The use of false lashes as well as the techniques used to apply them come...

The interpretation and use of ultrasound biomicroscopy (part 1)

1 October 2016 | | Cornea / External Eye Disease, Imaging, Retina / Uvea / Vitreous
Ultrasound Biomicroscopy (UBM) has become increasingly important for the diagnosis of a variety of anterior segment pathologies. Most ophthalmologists are familiar with conventional B-scan ultrasonography techniques, which operate at lower sound frequencies (7.5 to 20MHz). UBM is an ultrasound technique...

Herpes zoster ophthalmicus: a clinician’s perspective

25 January 2023 | | Ophthalmology, ONLINE EXCLUSIVE ARTICLES
Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...

NYU Langone Health performs world’s first whole-eye & partial-face transplant

15 November 2023 | NYU Langone, eye transplant, Face transplant, surgery, therapies, Aaron James, USA, Eduardo D. Rodriguez
Landmark whole-eye transplant is a major paradigm shift for potential vision therapies.

House of cards

3 August 2023 | | Ophthalmology
When I was a junior doctor in the late 1990s writing my first scientific papers, once each article was finished, I had to fill out an application form, print out multiple copies and then walk to the post office at...

Improving cataract efficiency: insights and learnings from expert practitioners

1 December 2022 | | Ophthalmology, Cataract and Refractive
An evening surgical meeting sponsored by Théa Pharmaceuticals Ltd brought together leading experts to share insights and experience on practice strategies to enhance the efficiency of cataract surgery. Streamlining patient flow to optimise capacity and efficiency Qasim Mansoor, Consultant Ophthalmic...

Improved efficacy expected with second-generation microinvasive glaucoma surgery (MIGS) devices

1 July 2015 | | Glaucoma
Microinvasive surgical approaches to primary open-angle glaucoma (POAG) offer minimally traumatic options for effective intraocular pressure (IOP) reduction in appropriately selected glaucoma patients. Increases in laser trabeculoplasty rates and wider adoption of glaucoma drainage device filtration procedures, together with the...