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BESTi: a new index to detect subclinical keratoconus

In this multicentre, case-control study, the authors develop a new index, named Boosted Ectasia Susceptibility Tomography Index (BESTi), to detect early cases of keratoconus. This index was derived from multiple logistic regression analysis of 22 variables of tomography scans. The...

Using a tumour registry to investigate optic nerve gliomas

This study is a retrospective comparative analysis. Patients with optic nerve glioma and pilocytic astrocytoma were identified through the Surveillance, Epidemiology and End Results (SEER) cancer registry covering a 42-year period using standardised codes. The following data was extracted: basic...

Differential diagnosis in cases of suspected neuroretinitis

Neuroretinitis is a form of optic neuropathy typically characterised by acute unilateral visual loss with optic disc oedema and macular exudates arranged in a star figure around the fovea (complete or partial star). The purpose of this study was to...

Diagnosis and management of orbital vascular malformations

This is an authoritative review of a controversial and difficult clinical area. The authors have experience of over 350 cases and provide a well-structured review of the classification and management of orbital vascular malformations. They emphasise the need to understand...

A surgical option for congenital ptosis

The authors describe a surgical technique to manage congenital ptosis. They present 30 patients with severe congenital ptosis, MRD1 varying between -2mm and 1mm. Intervention was carried out early to prevent amblyopia. All cases had surgery before age seven with...

House of cards

When I was a junior doctor in the late 1990s writing my first scientific papers, once each article was finished, I had to fill out an application form, print out multiple copies and then walk to the post office at...

The Global Vision Database

The overall goal of the Global Vision Database (GVD) [1] is to develop and deploy new and improved evidence on the prevalence of blindness and vision impairment (VI) globally. It is a repository which allows us to assess the causes...

The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Information booklet for eye drop use

On the basis that children may be more at ease and experience less discomfort and anxiety if provided with some control and choices, the authors developed an eye drop booklet in collaboration with children. This study describes the amount of...

‘Step Up For Nystagmus’ this Nystagmus Awareness Day

Monday 20 June, the Nystagmus Network marks Nystagmus Awareness Day by asking supporters to ‘Step Up For Nystagmus’ to raise awareness of this complex visual impairment.

In conversation with Robert F Walters, Orbis Trustee

Can you give us a brief overview of the organisation and its hope for the future? Orbis International is a global non-governmental organisation (NGO) which is dedicated to the prevention of blindness. We’ve now been going since 1982. We’re very...

Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation

An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...