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Gene therapy: perspectives from young adults with Leber’s congenital amaurosis
The authors present their telephone survey data of 10 patients with a mean age of 24.4 years regarding their opinion on gene therapy for their Leber’s congenital amaurosis. Patients were recruited at the Hospital for Sick Children, Toronto. Of the...ABDO responds to GOC research
New research published by the General Optical Council (GOC) shows an increase in public satisfaction in eyecare services.ABDO welcomes the RNIB's new eye care support pathway
The Association of British Dispensing Opticians (ABDO) welcomes the Royal National Institute of Blind People (RNIB) eye care support pathway.
Differentiating orbital cellulitis from non-specific orbital inflammation
This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...College of Optometrists responds to Labour’s partnership plans for eyecare
Shadow Health Minister, Karin Smyth MP, has outlined Labour’s plans to support improved eyecare services.
Tocilizumab in Graves’ orbitopathy
This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
Comparison between findings in ‘active’ or ‘healed’ giant cell arteritis
Giant cell arteritis (GCA) is the most common systemic vasculitis in older people and can cause devastating sight loss if untreated. Temporal artery biopsy is often relied upon for diagnosis by ophthalmologists, with a positive biopsy result indicating whether the...Glaucoma UK offers up to £50,000 for the Open Call Research Award 2024
Glaucoma UK accepts applications for the Open Call Research Award 2024, which offers up to £50,000 in funding for glaucoma-related research. This award invites both clinical and non-clinical researchers who aim to enhance our understanding of glaucoma, and improve outcomes for people living with the disease.
A mouse model for uveal melanoma
Uveal melanoma (UM) is the most common malignant tumour arising within the eye and is a severe threat for both sight and life, due to a high risk of metastasis. There are no animal models of UM, but the Tg(Grm1)...
RPE use similar pathway to regulatory T cells to inhibit immune response
Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....
