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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Analysis of ‘urgent’ cataract referrals from community optometrists in the West of Scotland

As elective cataract services restart post-COVID, how do we establish which patients should be a priority? The authors share their findings from a review of ‘urgent’ referrals received by the ophthalmology department in NHS Greater Glasgow & Clyde. The COVID-19...

Introduction of the Mydriasert insert at the Manchester Royal Eye Hospital

The authors report on a study to examine the effects of the Mydriasert insert on time, effects, patient comfort and tolerability at Manchester Royal Eye Hospital. Mydriasert is an insoluble ophthalmic insert indicated for mydriasis prior to ophthalmic surgery, which...

Addressing medical risk factors for diabetes and understanding the new systemic treatments

As global diabetes figures continue to rise, the importance of reducing the burden of macrovascular and microvascular complications of diabetes has never been so great. By 2025 it is estimated that five million people in the UK will have diabetes...

Redeployment during the COVID-19 pandemic: personal accounts from four ophthalmology trainees

We once believed that the coronavirus would not penetrate the safe confines of the United Kingdom, like so many outbreaks before this. Once the news came that this pandemic descended into our hospitals, the anxieties about redeployment began. Many of...

The assessment of pupils and 
pupillary reactions

Understanding pupillary reactions is vital in understanding basic neuro-opthalmology. It is a skill required in eye casualty, clinics and perhaps most importantly, exams. To start at the beginning, the pupil is the central aperture of the iris, its size controlling...

The paediatric cataract: an overview of the embryology and pathophysiology

In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...

Understanding vasoproliferative retinal tumours

Syed Irtiza Ali Shah explores this rare and unusual condition through a fascinating case presentation. Vasoproliferative tumours of the retina (VPTR) are a vascular mass with an associated exudative retinopathy alongside the presence of minimally dilated feeder vessels. This is...

Typical and atypical optic neuritis – diagnosis and initial management

Optic neuritis is a relatively common presentation to ophthalmologists in the acute setting. The vast majority are cases of ‘typical’ optic neuritis (ON) but a smaller group of conditions, so-called, ‘atypical’ optic neuritides require a different work-up and management strategy....

Life as a Global Citizen Consultant Ophthalmologist: a personal view of working in Scotland and Tanzania

Global Citizen post - a new challenge I was looking for a new challenge. I had been in the same consultant post with a subspecialty interest in paediatrics and strabismus for 17 years and was rattling around in an empty...

Investigating the link between corneal clarity and statin use

Transparency is a vital attribute of the cornea, necessary in preserving healthy vision. Maintaining this requires the collective input of the various layers of the cornea. Mostly, the layers implicated in this are the corneal stroma and endothelium [1]. Our...

Increasing access to eye care through community outreach clinics in Uganda

There has been a VISION 2020 LINK between Mulago Hospital and Makerere University in Kampala, Uganda and the Royal Free Hospital, London, since 2010. There have been regular training visits between teams from the eye departments at Mulago and the...