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Can retinal layer thickness predict the progression of disability in MS?
This is an observational retrospective cohort study presenting the data of 188 patient diagnoses with multiple sclerosis at two specialist centres. All included patients were adults below the age of 70 years, stable on their disease modifying treatment for at...
Association between serum levels of testosterone and estradiol with meibomian gland assessments in postmenopausal women
This study aims to reveal any correlation between serum levels of testosterone and estradiol in postmenopausal women with meibomian gland dysfunction. Postmenopausal subjects were defined as amenorrhoea for at least one year with low follide stimulating hormone (FSH) and estradiol....
Optical coherence tomography in patients exposed to vigabatrin
Vigabatrin is used to treat epilepsy and can lead to increased levels of gamma-aminobutyric acid (GABA) in the brain and in the retina leading to binasal visual field defects. Although not the first line of treatment for adults it is...The challenge of chorioretinal folds in virtual eye clinics
Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...Manchester Royal Eye Hospital first in UK to use ultra-wide field OCT angiography machine in patient facing setting
Manchester Royal Eye Hospital announces it is the first in the UK to utilise the ultra-wide field OCT angiography machine, the Xephilio OCT-S1 from Canon, in a patient facing setting.
Retinal Pharmacotherapeutics (Developments in Ophthalmology)
Retinal Pharmacotherapeutics is volume 55 in the ‘Developments in Ophthalmology’ series released by Karger. As the name of the series suggests it aims to explore current and future developments in retinal therapeutics. The book itself is split into six main...Typical and atypical optic neuritis – diagnosis and initial management
Optic neuritis is a relatively common presentation to ophthalmologists in the acute setting. The vast majority are cases of ‘typical’ optic neuritis (ON) but a smaller group of conditions, so-called, ‘atypical’ optic neuritides require a different work-up and management strategy....
Air toxicity on retinal pigment epithelium
This study investigated the potential toxic effects of air on primary human retinal pigment epithelial (RPE) cells in vitro. Clinically during pars plana vitrectomy air is used as either a temporary tamponade during air-fluid exchange or mixed with gas to...What's trending Feb/Mar 2022
A round-up of the eye-related hot topics that have been trending over the last few weeks. British man fitted with 3D printed eye Steve Verze of London has required a prosthetic eye for over 20 years. On 25 November 2021,...
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
