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Somatostatin protects retinal pericytes
Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...
Changes in the choroid after atropine for amblyopic and fellow eyes
The purpose of this study was to compare the effects of atropine on the thickness and structure of the choroid between amblyopic and fellow eyes. This study included 16 patients: five males, 11 females. Median age at ocular coherence tomography...
Driving with the use of spectacle mounted telescopes (bioptics)
The authors discuss the current perspectives of spectacle mounted telescopes (bioptics) whilst driving among patients with visual impairment. The history, design and driving laws surrounding the use of bioptics is discussed in detail. In 1977, William Feinbloom developed a bioptic...
Who will benefit from cataract surgery?
The need for cataract surgery is expected to rise dramatically in the future due to the increasing proportion of elderly citizens and increasing demands for optimum visual function. The aim of this study was to provide an evidence-based recommendation for...
Using OCT to screen and monitor Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...
Effective contrast ratio as a measure of binocular visual perception
The authors used a binocular phase combination paradigm to quantitatively evaluate and compare the binocular visual perception of normal individuals and patients with different types of strabismus to understand the binocular visual perception of patients with strabismus and evaluate whether...Pituitary adenoma causing compression of the optic chiasm
A 21-year-old girl presented to her general practitioner (GP) with a three-month history of headaches, becoming more frequent and associated intermittent vomiting that did not improve with simple analgesics. There was a strong family history of migraines. She was initially...
Same day air bubble removal after DSEK/DSAEK
A complete air removal on same day as descemet’s stripping endothelial keratoplasty (DSEK/DSAEK) leads to prompt restoration of the anterior chamber and thus has been hypothesised to assist with the recovery of endothelial function and promote graft adhesion. The results...
Postop improved fusion and stereopsis in IDEX
This study aimed to evaluate changes in binocular visual function in patients with different ages before and after surgery to explore the optimal timing of intermittent exotropia surgery. The study comprised 28 females and 25 males. Fifty-three patients were split...
Brn3b neuroprotective effect in rat glaucoma model
An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...
Do operative interventions for IIH improve visual function?
The authors of this paper reviewed patient case notes to determine visual outcome following shunt surgery for idiopathic intracranial hypertension (IIH). A retrospective case notes review was conducted for 50 patients who underwent shunt surgery for IIH. Outcome measures included...
