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Cytotoxic effect of voriconazole on human corneal epithelial cells

Voriconazole is a second-generation synthetic derivative of fluconazole with broadened antifungal spectrum. It is becoming the drug of choice for fungal keratitis. Voriconazole eye drops are not available commercially, thus have to be prepared by diluting the intravenous formulation containing...

The long-term effects of AREDS on AMD progression

The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...

Brolucizumab in age-related macular degeneration, HAWK Study

The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

The most frequent complaints and claims in ophthalmology – a Medical Protection Society (MPS) analysis

The authors look at the reasons behind medico-legal cases reported to MPS and share key learning points. Complications following ophthalmology surgery are rare, however, medico-legal cases are not uncommon due to the significant impact they can have on patients’ lifestyles....

Implementing technology to improve global eye health

Technological innovation is providing new solutions to transform global eye health [1–5]. In particular, research towards the development of artificial intelligence (AI) tools in ophthalmology has gained pace in recent years. However, there has been little research relating to its...

Can 3D facial imaging improve patient management in disfiguring eye disease?

Fight for Sight is the leading UK charity funder of eye research. Since the 2013 Sight Loss and Vision Priority Setting Partnership we have encouraged our researchers to work on priorities jointly identified by people affected by sight loss and...

My experience of the transition into a specialist orthoptist role

Michelle Dent discusses the process of transitioning into a new role and the pros and cons along the way. An opportunity arose for a permanent, full time, band 7 specialist role in the medical retina (MR) team in the Newcastle...

A personal reflection: working at the International Centre for Eye Health from 2006–2024

I feel incredibly fortunate to have been working part-time at the International Centre for Eye Health (ICEH) [1] since 2006. Earlier in my career, the responsibilities of work and a growing family made this merely an aspiration, and apart from...

Development of a modern surgical simulation suite to promote safer ophthalmic surgical training

For trainees, having access to surgical simulation equipment is more important than ever. The authors describe the creation of a bespoke teaching and training suite in Glasgow to help trainees develop their skills and promote surgical excellence. Simulation has become...

NICE drugs: an update on what’s good to go

Treatment options recommended by the National Institute for Health and Care Excellence (NICE) must be readily available for use in the NHS of England and Wales. This article provides an overview of recent guidance from NICE and summary advice issued...

2030 In Sight: Ending avoidable sight loss

Over 2.2 billion people on our planet live with visual impairment or blindness with 1.1 billion unable to access affordable treatment. The 2030 In Sight sector strategy led by the International Agency for the Prevention of Blindness (IAPB) is an...

What's trending Apr/May 2020

#punch #shark Nick Minogue, a 60-year-old New Zealander, was surfing off Pauanui Beach when he was attacked by a Great White Shark. Luckily, he recalled advice that sharks are vulnerable if hit in the eyes or the nose. His first...