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Care pathway to imaging delays for acute oculomotor nerve palsies

A retrospective chart review is presented with the aim of evaluating arterial imaging in cases of third nerve palsy. The study reviewed patients seen with a suspicion of or a final diagnosis of third nerve palsy over a seven-year eight-month...

IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

Ocular manifestations of Whipple’s disease

In this retrospective review of 217 patients with Whipple’s disease (WD), the authors reviewed the presentations of those with ocular manifestations. Ocular signs of WD are under recognised, frequently resulting in misdiagnosis and mismanagement. Mayo Data Explorer, a Mayo Clinic...

The Sclera and Systemic Disorders (3rd Edition)

An interesting historical introduction captures the reader’s attention as the journey begins into exploring the peculiarities and pathologies of ‘dura tunica of Vesalius’, a term coined by anatomists of the middle ages. This refers to what we today identify as...

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...

The impact of obstructive sleep apnoea monitoring functionality on smartwatches: a new frontier for ophthalmologists

Dawn of a new era in wearable technology? Smartwatches have really stepped up their game and have evolved from telling time to keeping an eye on our health. In February 2024, the United States Food and Drug Administration (FDA) gave...

Herpes zoster ophthalmicus: the essentials

Herpes zoster, also referred to as shingles, is a common infection most typically caused by the reactivation of varicella zoster virus that lies dormant (sometime for decades) in the dorsal root nerve ganglion following primary chickenpox infection [1]. In 10-20%...

Cytomegalovirus retinitis post intravitreal triamcinolone in an immunocompetent patient with juvenile glaucoma

Figure 1: Fundus photograph shows active CMV retinitis four weeks after IVTA in the right eye. Figure 2: Fundus photograph of the left eye with no CMV retinitis; atrophic disc as a result of juvenile glaucoma. Case report A 29-year-old...

Reduction of severe visual loss and complications following IAC for RB

This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...

The management of chronic uveitis

A 40-year-old company executive is referred from another unit with recurrent anterior and posterior uveitis for 12 months and the inflammatory markers are raised. Review of systems This is a case of chronic uveitis which needs a thorough workup and...

OCTA in diabetic macular oedema treated with intravitreal aflibercept (DOCTA Study)

Central vision loss due to diabetic macular oedema (DME) can be attributed not only to presence of the macular oedema itself but also, in some cases, to alterations of the foveal avascular zone (FAZ). The DOCTA trial was a longitudinal,...

Task shifting for eye care in Eastern Africa

More than eight million people suffer with trichiasis due to trachoma globally, but less than 160,000 receive surgery per year even though “S” is a key aspect of the elimination of blindness due to trachoma as part of the WHO...