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MicroRNAs in cataract

In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...

Update on primary angle closure glaucoma

This review article considers primary angle-closure glaucoma which is responsible for half of glaucoma-related blindness worldwide. Angle closure is characterised by appositional contact between the iris and trabecular meshwork. It tends to develop in eyes with shallow anterior chambers, anteriorly...

Burden of caregiving for children with eye diseases

This review was conducted to examine the existent literature and characterise the psychological impact of caregiving for children with various eye diseases. The factors associated with the burden of caregiving were discussed in the context of each eye disease identified....

Top cited 100 publications in paediatric ophthalmology

The author identified the top 100 cited publications in paediatric ophthalmology in an effort to identify which topics are most strongly represented and potential areas where further research is needed. An ISI Web of Science database search was conducted in...

Rare case reports of benign optic glioma in adults with clinically aggressive nature

Primary optic nerve gliomas are most commonly benign and occurring in childhood. Malignant optic gliomas occur in adulthood and follow an aggressive course usually leading to blindness and death within months. This paper describes the clinical and histopathological features of...