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Microsporidia-induced stromal keratitis: a new cause of presumed immune stromal (interstitial) keratitis

This is a non-comparative retrospective observational case series from India from 1 October 2020 to 31 January 2021. The inclusion criteria were: (1) presence of nummular / coin shaped lesions with at least one >2mm in size and / presence...

Steroid implants in the treatment of post-epiretinal membrane peel macular oedema

This is a retrospective review of 39 eyes of 37 patients treated with Ozurdex® (intravitreal dexamethasone implant) for persistent post-operative cystoid macular oedema (CMO) following vitrectomy and idiopathic epiretinal membrane (ERM) peeling. The 0.7mg implant was injected in each eye...

Cornea, 2-Volume Set: Fundamentals, Diagnosis, Management and Surgery of the Cornea and Conjunctiva (4th Edition)

Originally published in 1997 as a comprehensive set of three volumes on cornea and external eye disease, this two volume edition, published at the end of 2016, offers “a complete multimedia resource, in print, online, eBook and video format”. There...

MicroRNAs in cataract

In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...

Autophagy in lens mitochondria loss

The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Limbal melanocytes and the stem cell niche

The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...

Risk factors for lens dislocation post cataract surgery

This retrospective cohort study in Korea assessed the risk factors for intraocular lens (IOL) dislocation. They used national data of 2,162,191 patients who had had cataract surgery between 2009 and 2016. They excluded any patient who had an IOL dislocation...

Can closing the eyelid during riboflavin induction phase of crosslinking increase corneal thickness?

Corneal crosslinking (CXL) with riboflavin and UVA irradiation is the standard treatment for preventing progression of keratoconus. Thinning of the cornea during the riboflavin loading phase was reported in previous studies which used riboflavin with dextran. A minimum stromal thickness...

Comparison of ketorolac 0.4% and nepafenac 0.1% for the prevention of CMO after phacoemulsification

This is a prospective randomised clinical trial study including patients older than 40 years with age related cataract and normal ophthalmic examination. The patients are randomised into three different groups and the objective of the study is to compare the...

Results after 1.4mm biaxial cataract surgery and implantation of a new aspheric intraocular lens

The aim of this study was to analyse the clinical outcome and higher-order aberrations (HOAs) after 1.4mm biaxial micro incision cataract surgery (B-MICS) and implantation of a new aspheric intraocular lens (IOL). A total of 157 eyes of 106 patients...

Accelerated (9mW/cm2) corneal collagen cross-linking for keratoconus

This is one of many studies published / to be published on corneal collagen cross-linking that has a treatment time of 10 minutes compared to the previous Dresden protocol of 30 minutes to halt progression of keratoconus. Much has changed...

Mini DMEK for acute hydrops

This is a retrospective analysis of three patients who underwent mini DMEK for massive corneal hydrops in acute keratoconus. DMEK graft was trephined or trimmed according to the size and the shape of the gap in the patient’s Descemet membrane...