You searched for "epithelium"
Reduced blood flow and age-related macular degeneration
1 August 2014
| Khadijah Basheer
|
EYE - Vitreo-Retinal
This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...
Microperimetry of subretinal drusenoid deposits
1 February 2014
| Bheemanagouda Patil
|
EYE - Vitreo-Retinal
Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...
HtrA1 enhances cell senescence
1 December 2013
| Graham Wallace
|
EYE - Vitreo-Retinal
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
Features, treatment and prevention of conjunctival inclusion cysts
Conjunctival inclusion cyst is a rare complication of strabismus surgery and generally develops at the point of muscle reattachment, caused by implantation of conjunctival epithelium. The authors aimed to determine the rate of its development after strabismus surgery and consider...Quiz Oct/Nov 2024
History An 83-year-old female was previously treated by surgical excision and plaque brachytherapy for her left conjunctival lesion. She presented to her ophthalmologist with a recurrence some years later and underwent a lid sparing orbital exenteration, which was sent to...Recurrent corneal erosions secondary to isotretinoin use
Isotretinoin (13–cis-retinoic acid) is the first line treatment for moderate to severe nodulocystic or papulopustular acne [1,2]. Although it is a safe medication, it has several adverse side-effects, including ophthalmic manifestations, as shown in Table 1 [3]. These side-effects need...Quiz Dec/Jan 2023
1 December 2022
| Christopher Bell, Elizabeth James
|
EYE - General
History A 35-year-old female presented to the emergency eye clinic with an acutely red, painful, photophobic left eye. She was a contact lens-wearer but denied swimming, showering, or sleeping in her lenses. She resided on a farm and worked as...
Histopathology-guided management of ocular surface squamous neoplasia (OSSN) with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy
11 January 2024
| Jonathan Chan
|
EYE - Pathology, EYE - Oncology
|
conjunctiva, eye (globe), pathology, salivary gland
This is a retrospective interventional consecutive case series of 42 eyes of 42 patients with OSSN with histopathologically proven corneal stromal and / or scleral invasion following excision biopsy. The mean tumour basal diameter was 9.3mm and thickness of 3.1mm...
CD40L activation of human RPE cells
1 August 2018
| Graham Wallace
|
EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...
Preoperative RPE alterations in macular holes
1 April 2017
| Saruban Pasu
|
EYE - Vitreo-Retinal
This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...
Effect of anti-VEGF treatment on PED morphology
1 June 2015
| Jaya Myneni
|
EYE - Vitreo-Retinal
This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...
Feb/Mar 2015 Quiz 2
1 February 2015
| Hardeep Singh Mudhar
|
EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 60-year-old white Caucasian male, with a history of acne, presented with slate grey pigmentation of his upper forehead, pre-auricular skin, peri-oral area, forearms and shins. The conjunctivae showed bilateral lower tarsal conjunctival multiple black dots. One of these...
