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Code-Free Deep Learning: a step into the future of ophthalmology

A new focus has arisen within the research domain of artificial intelligence (AI) in healthcare called code-free deep learning (CFDL), and recent research demonstrates that ophthalmology is becoming one of the leading specialties in this field. Artificial intelligence (AI) is...

The original smooth operator: Sir Robin Millar

As an early 80s kid, if you lacked sufficient pocket money, building a music collection entailed recording your favourite songs off the radio with a cassette deck and hoping the presenter didn’t interrupt at any point, with a finger hovering...

Headaches in ophthalmology (part 2)

Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...

Rituximab efficacy for juvenile idiopathic arthritis

This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....

Normal reference values for the RETeval device

The purpose of this study was to provide normative data of full-field electroretinography (ERG) responses in the paediatric population using the RETeval device in healthy children with normal retinas. This was a prospective study of 38 eyes of 20 patients...

Light reflex in preterm infants

In this study, the pupillary size and light reflex was examined in premature infants using infrared video-pupillography and stimuli of red and blue light. Only eyes of infants without retinopathy of prematurity were included in the study. Pupillary light reflexes...

Microbiology, risk factors and outcomes of microbial keratitis in Sydney, Australia

The authors present a retrospective case series including all patients with microbial keratitis and ocular surface diseases (OSD), including dry eye, blepharitis, Stevens-Johnson syndrome and / or ocular cicatricial pemphigoid, over a five-year period between 2012 and 2016. A total...

Do topical steroids improve visual outcome in the treatment of bacterial keratitis?

The use of topical corticosteroids as an adjunctive treatment to antibiotics in the management of bacterial keratitis remains a controversial issue. The results of the Steroids for Corneal Ulcers Trial (SCUT) – a randomised, double-masked, placebo-controlled trial that recruited patients...

Non-contact-lens-associated acanthamoeba keratitis

This retrospective study was done to study the clinical presentation and microbiological results of non-contact-lens-related acanthamoeba keratitis (AK). One hundred and ninety-four patients with microbiological / histopathological diagnosis of AK over four years were included. All patients had corneal scrapings...

RPE use similar pathway to regulatory T cells to inhibit immune response

Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

Bacterial keratitis through the window of the known unknowns

This review article provides an up-to-date summary of current challenges in research and management of bacterial keratitis. The authors highlight that there is no current agreement on the criteria that should define bacterial keratitis; the role of investigation is unclear,...