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Ocular ischaemic syndrome in a rat model
Ocular Ischaemic syndrome is a devastating eye disease caused by severe carotid stenosis. This study’s purpose was to develop a reliable rat model for this syndrome by subjecting rats to common carotid artery occlusion and sham surgery. Rats were assigned...
Avastin vs. Volon A for diabetic macular oedema
This prospective randomised interventional clinical trial compared 30 diabetic patients with macular oedema treated with either intravitreal injections of bevacizumab (Avastin) or triamcinolone (Volon A). One group initially received three injections of 2.5 mg Avastin in monthly intervals whilst the...
Latanoprost in the treatment of congenital glaucoma
The aim of this study was to investigate the glaucoma control of latanoprost therapy in primary congenital glaucoma (PCG) and assess the factors affecting long-term outcome. Eighty-one eyes of 44 patients with PCG and 42 eyes of 29 patients with...
The long-term effects of AREDS on AMD progression
The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...
Review of chalazion treatment
Even though chalazion is a common eyelid lesion, there is lack of consensus on a treatment algorithm. Conservative management includes lid hygiene and warm compresses and, in some cases, steroid ointments for two to three weeks. More invasive options for...
Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations
Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...Unexpected diagnoses – stroke in children and homonymous hemianopia
We present the case of a 12-year-old child presenting with a few days history of left-sided visual loss. Upon further investigation with magnetic resonance imaging (MRI) she was unexpectedly diagnosed with a right-sided chronic posterior cerebral arterial territory infarct, causing...Advanced Glaucoma Surgery Course in Africa through the Juba-Bournemouth VISION 2020 LINK
In order to enhance specialist skills, particularly for South Sudan, the Juba-Bournemouth VISION 2020 LINK has been offering week-long intensive ophthalmic specialist training for the last three years, in collaboration with the University of Nairobi, the College of Ophthalmology of...
Retinal vessel diameter in pseudoexfoliation
Pseudoexfolation (PEX) is characterised by deposition of fibrillary extracellular material on ocular and extraocular tissue. Studies have shown that deposition in vascular structures cause hypoxia and ischaemia. In the eye, a decrease in blood supply to the optic nerve can...
Treat and extend for PCV
This South Korean study investigated the efficacy of a treat and extend regimen (TER) using ranibizumab to treat polypoidal choroidal vasculopathy (PCV). Twenty-nine eyes were included in this retrospective case note review. Of these, five eyes had been treated with...
