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1822 results found

Prognostic information for PRP-naive patients

The Diabetic Retinopathy Study group demonstrated that pan retinal laser photocoagulation (PRP) reduces severe vision loss by up to 50% in cases of proliferative diabetic retinopathy (PDR). The authors of this current study aimed to provide information for laser naive...

Squamous metaplasia of conjunctival epithelial cells with soft contact lens wear versus non-lens wearers

Conjunctiva is composed of non-squamous epithelial cells interspersed with goblet cells, which is a secretory epithelium. Squamous metaplasia is a transformation to non-secretory epithelium, ‘keratinised’ and enlargement of the conjunctival non-goblet cells and relatively shrunken nuclei are seen on impression...

Blinking and driving

Spontaneous blinking is dependent on cognitive processes and is regulated by a central pacemaker that is highly sensitive to the attention demands and cognitive workload of the visual task in hand. There is evidence of a variability in the frequency...

Emerging developments in dry eye

An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...

In conversation with Andrena McElvanney (President, MCLOSA)

We spoke to Andrena about MCLOSA's annual meeting this November, key developments in cornea and external eye disease, and plans for the association’s 30th anniversary. Andrena McElvanney (top, second from right) and the OSI council members. The Medical Contact Lens...

Ocular Dirofilariasis: a diagnosis on the rise?

Dirofilaria repens is one of 40 species of Dirofilaria. It is a zoonotic filarial nematode that commonly impacts dogs, however, human infection can occur through affected organs like skin, lung and eyes [1]. Although, there have been case reports of...

A single intravitreal bevacizumab in the treatment of breast carcinoma related choroidal metastasis

Case report Choroidal metastasis represents a common form of intraocular malignancies occurring in up to 10% of patients with systemic metastasis [1]. The most common primary sites of ocular metastasis are breast carcinoma in women and lung carcinoma in men,...

Retinopathy of prematurity treatment in the South West of England: long-term outcomes 1997-2008

Retinopathy of prematurity (ROP) is a condition that affects the developing retinal vascular system of pre-term babies. If left untreated, ROP can lead to severe visual impairment. The severe visual impairment caused by untreated ROP can be prevented by screening...

Feb/Mar 2018 Quiz

History A 48-year-old farmer with gradual worsening vision in her only eye was referred by her optician. She had recently moved to the UK and required an interpreter during consultation. She seemed to have had vision problems since childhood. Although...

OCTA to measure surgical haemodynamic changes

This study used the optical coherence tomography angiography (OCTA) technique to evaluate possible haemodynamic changes after horizontal rectus muscle surgery in 32 eyes of 16 patients; nine male, seven female. Recession / resection surgery was undertaken for two horizontal rectus...

OCTA to measure surgical hemodynamic changes

This study used the optical coherence tomography angiography (OCTA) technique to evaluate possible hemodynamic changes after horizontal rectus muscle surgery in 32 eyes of 16 patients; nine male, seven female. Recession / resection surgery was undertaken for two horizontal rectus...

Corneal stroma modelling under hypoxic conditions

The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...