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CMV assessment

This is a retrospective, cross-sectional review of medical records from a consecutive series of patients with AIDS-related cytomegalovirus (CMV) retinitis who were examined at five HIV disease clinics in Yangon, Myanmar, in November 2006. All patients with CD4+ T lymphocytes...

Is serum ACE useful in diagnosing sarcoidosis in uveitis patients?

This retrospective clinical notes review assesses whether serum angiotensin converting enzyme (ACE) is useful in the diagnosis of sarcoidosis in patients presenting with uveitis. There were 1035 consecutive subjects presenting with uveitis as part of baseline investigations had a serum...

Comparison of visual fields between migraine and tension type headaches

The aim of the study was to compare the clinical features and visual fields of patients with migraine without aura and tension type headache. Visual fields were assessed whilst the patients were having an attack of pain and tested using...

Combined ranibizumab and ablative therapy for Coat’s disease

The aim of this study was to observe the efficacy of intravitreal ranibizumab (IVR) combined with laser photocoagulation or cryotherapy, for Coats’ disease. Patients younger than 16 years of age who were diagnosed with Coats’ disease were included in this...

Repeated orbital decompression surgery

This is a retrospective review of nine redo orbital decompressions in six patients. All operations were performed for dysthyroid optic neuropathy, both initially and when repeated. The interval between first and redo decompressions varied from one to 15 years and...

Surgical outcomes in third nerve palsy

The authors of this article explore the factors associated with successful surgical outcomes in third nerve palsy, which is known to be difficult to treat. A number of case notes were reviewed for patients who underwent surgery or botulinum toxin...

Surgical success rates in abducens palsy management

The aim of the study was to identify factors associated with surgical outcomes in isolated abducens palsy. To achieve this goal the authors reviewed the records of adult patients with abducens palsy who underwent strabismus procedures during a fourteen year...

Methotrexate and mycophenolate mofetil for non-infectious uveitis

This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...

Long-term outcomes for hereditary retinoblastoma

Earlier diagnosis and more rigorous treatment regimens have contributed to better outcomes for patients with retinoblastoma. This study looked at 24 patients with hereditary bilateral retinoblastoma treated with systemic chemotherapy during a ten year period (2001-2011). The medical notes were...

Pterygium ocular surface temperature

This prospective study investigated the ocular surface temperature in patients with pterygia compared to those with dry and healthy eyes respectively. Previous studies have shown that patients with dry eyes show a significant decrease in ocular surface temperature on sustained...

High myopes with POAG and IOP fluctuations

The authors describe a prospective study of 80 eyes of Chinese patients with primary open-angle glaucoma (POAG) on prostaglandin analogues to investigate if those who also have high myopia exhibit greater short-term intraocular pressure (IOP) fluctuations at resting conditions over...

Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis

A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.