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Extraocular muscle disinsertion outcomes for large angle strabismus
The authors present a case series of patients who underwent surgical extraocular muscle (EOM) disinsertion for severe cranial nerve palsy or thyroid eye disease including 12 patients (13 eyes: 10 male, three female). There was one bilateral case – bilateral...
Outcomes for acute acquired non-accommodative comitant esotropia
Outcomes are reported in a retrospective review of 338 patients with acute acquired non-accommodative comitant esotropia (AACE). Mean age at presentation was 12.60 ±9.37 years and 220 were male, 118 female. Best corrected visual acuity was 0.2 ±0.29 logMAR overall;...
Cataract progression after Nd-YAG laser iridotomy in primary angle-closure suspect eyes
A total of 889 of eligible bilateral primary angle-closure suspect (PACS) patients were recruited from the Zhongshan Angle Closure Prevention Trial. One randomly selected eye received laser peripheral iridotomy (LPI), while the fellow remained untreated. Cataract was graded by the...
BTA injection to treat convergence insufficiency
The outcomes of patients with convergence insufficiency (CI) treatment with botulinum toxin A (BTA) in one or both lateral rectus muscles are reported. This was a retrospective study of 23 patients; eight males, 15 female, mean age 59 years (range...
Outcomes of suture-less vs. sutured wound closure for paediatric cataract surgery
In this study the authors aimed to compare the incidence of postoperative complications between cases of suture-less and sutured wound closure in paediatric cataract surgery. This was a retrospective study of children aged <18 years and included 116 eyes of...
Surgical complications of ReLEx
Femtosecond laser refractive lenticule extraction (ReLEx) is a novel procedure for treatment of myopia and myopic astigmatism, which eliminates the use of microkeratome and excimer laser. Currently there are two techniques: FLEx – femtosecond lenticule extraction (similar to conventional LASIK)...
RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
Systemic anti-inflammatory versus fluocinolone acetonide intraocular implant
In the Multicenter Uveitis Steroid Treatment (MUST) trial, 255 patients with intermediate uveitis, posterior uveitis or panuveitis were randomised to either fluocinolone acetonide intraocular implant or systemic corticosteroid therapy which was supplemented with immunosuppression if required. Patients were followed up...
Ozurdex wound leakage
This letter to the editor describes two cases of wound leakage after Ozurdex injection. The first case is a man who had four previous injections for an underlying diagnosis of chronic serpiginous choroiditis, who was also on a course of...
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
Intravitreal aflibercept for diabetic macular oedema
The VISTA and VIVID randomised phase 3 trial were designed to compare the efficacy and safety of intravitreal aflibercept injections versus laser photocoagulation for diabetic macular oedema (DMO). A total of 872 patients with centrally involving DMO were recruited, and...
