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Comparison of ganglion cell thinning in glaucoma vs. macular hole repair
This prospective study compared the changes in the photopic negative response of the focal macular electroretinogram (fmERG) caused by retinal ganglion cell complex (GCC) thinning at the macula between patients with open angle glaucoma (OAG) and 12 months after successful...
Acute retinal necrosis: an Indian experience
The authors of this retrospective study aimed to provide clinical outcomes in 62 eyes of 53 patients presenting with acute retinal necrosis. All eyes received intravenous acyclovir (10mg/kg tds) for 7-10 days followed by oral antiviral therapy (valaciclovir 1g tds...
Should intravitreal steroids be used in the initial treatment of post-op endophthalmitis?
Endophthalmitis following cataract surgery is one of the most feared complications, and can have significant impact on the visual outcomes of patients. The role of steroids in the management of endopthalmitis is controversial. The aim of this paper was to...
Outcomes of corneal cross-linking in paediatric patients compared to fellow untreated eyes
This retrospective cohort study evaluated long-term visual, refractive, topographic and safety outcomes of corneal cross-linking (CXL) in patients younger than 18-years-old with keratoconus. The study included all consecutive paediatric patients who underwent epithelium-off CXL treatment for keratoconus at the study...
PRN Ranibizumab verses continuous aflibercept in UK clinical practice
This was a multicentre (21 UK hospitals), national EMR study on treatment naïve nAMD eyes, undergoing predominantly as needed (PRN) Ranibizumab or continuous (fixed or treat and extend - (F/TE)) Aflibercept (Af). The primary outcome was change in vision at...
Smartphone based visual acuity
Smartphone technology is becoming widely available to all age groups and settings. Apps using Snellen acuity charts are widely available and this study evaluated the equivalence of a smartphone-based visual acuity chart with a standard 6m Snellen visual acuity (6SVA)...
Long-term effect of gene therapy on Leber’s congenital amaurosis
After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...
Features of Behcet’s disease
This is a retrospective single centre study from Paris, France, between the periods of 1986 to 2015. Twenty-nine out of 217 (13.3%) neuro-Behcet’s disease (NBD) patients presented with neuro-ophthalmic manifestations (55% of men and mean age of 28 years). Sixteen...
Cavernous sinus thrombosis and orbital cellulitis
This is a report of six cases of combined orbital cellulitis and infective cavernous sinus thrombosis, with a literature review. The average age was 39 years, four were male and two were intravenous drug users. All had sinusitis, usually involving...
Ptosis procedure compared to upper blepharoplasty on dry eye syndrome
In this prospective, comparative case series, the authors compare the effect of combined blepharoplasty and Muller muscle conjunctival resection (MMCR) to an upper blepharoplasty in dry eye syndrome. The study was approved by the local institutional review board and participants...
Quality of life concerns after uveal melanoma diagnosis
The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...
