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PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...
Large collar diameter Jones tubes
This is the first report of the success rates of frosted Jones tubes with larger diameter, 4.5 or 5mm collars. This is a retrospective review of 29 eyes of 25 patients who underwent insertion of a large diameter collar frosted...
Surgery for acquired distance esotropia
The purpose of this study was to evaluate the outcome of this surgical approach in the treatment of divergence insufficiency esotropia. This was a retrospective review of 18 patients aged on average 49.6 years; 77% were female. Preoperatively the distance...
Testing fusional amplitude
The purpose of this study was to evaluate the effects of varied testing distance and order of testing on fusion amplitudes in subjects with normal eye examinations, along with impact of examination encouragement and subject level of alertness. Average age...
Chloral hydrate sedation
A systematic review of literature sourced from PubMed, EMBASE, ISI, Web of Science, Scopus, CENTRAL, Google Scholar and Trip database to 1 October 2015, about the safety and efficacy of chloral hydrate (CH) by meta-analysis of randomised controlled trials (RCTs)...
CSD-OCT detection of minimally visible retinoblastoma
This paper reports minimally visible tumour recurrence that was detectable on spectral domain OCT (SD-OCT) in a two-month-old infant who had a diagnosis of bilateral familial retinoblastoma. The infant was treated with IVC for six cycles with vincristine, etoposide and...
IOL cataract surgery 7-24 months
The purpose of this study was to present the long-term outcome of IOLs in paediatric patients who received cataract surgery aged seven to <24 months. This was retrospective study with minimum follow-up of 12 months for 27 patients (28 eyes)....
IO overaction surgery
This study aimed to compare the effectiveness of two surgical methods on the correction of inferior oblique overaction (IOOA). This was a retrospective study of 99 eyes of 56 patients; 47 myectomy and 52 anterior transposition procedures. Mean age was...
International variations in ROP treatment
A retrospective cohort review of 48,087 premature infants weighing <1500 gm between 24 to 27 weeks gestation, from 11 high income countries in Australia, New Zealand, Canada, Finland, Israel, Japan, Spain, Sweden, Switzerland, Tuscany (Italy) and the UK . By...
The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Medical malpractice in uveitis: a review of clinical entities and outcomes
This paper presents a retrospective review of malpractice verdicts, rulings and settlements in the United States. Twenty-five cases of uveitis-related litigation spanning 1971-2014 were identified from the database representing 2.3% of all cases. Forty-eight percent of the cases were infectious....
