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High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema
The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...
Are corneal guttata an additional risk factor in complicated cataract surgery needing a future corneal transplant?
This registry-based cohort study from Sweden utilised data from the Swedish National Cataract Registry and the Swedish Cornea Transplant Registry. Patients who underwent phacoemulsification with a posterior intraocular lens between 2010 and 2012 numbered 192,476. Of these cases, 288 underwent...
Efficacy of combined vitrectomy with intravitreal corticosteroid injection for ERM
In this study the authors evaluated the efficacy of vitrectomy combined with corticosteroid injection for idiopathic epiretinal membrane (ERM). A systematic literature review was conducted by searching three electronic databases, PubMed, Embase and Medline, up to 2020 for relevant studies....Feb/Mar 2016 Quiz 2
History A 30-year-old male presents with a phthisical left eye and undergoes enucleation. He has some lesions in his right eye that are under ophthalmic surveillance. Figure 1 is a low power of the enucleation. Figures 2, 3 and 4...
CD73 in aggressive basal cell carcinoma
This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...
Hidden spread of sebaceous cell carcinoma
This was a review of 29 patients who had undergone orbital exenteration for sebaceous cell carcinoma. Prompted by the increasing use of topical treatments for intraepithelial disease, the authors were keen to discover the frequency of spread of tumour cells...
Anatomical variations of the nasolacrimal system
The authors report a retrospective observational case series of 734 dacryocystography images; 689 from adult patients and 45 from paediatric patients. Of these 734 images, 35 (4.8%) were found to have an anatomical variant where the nasolacrimal duct emerged from...Pathological myopia: a trainer’s perceptive
High myopia is defined as myopic refraction of greater than -6 dioptres with an axial length greater than 26.5mm, while pathological myopia is myopic refraction with posterior pole degeneration [1]. These degenerative changes can affect a young population and in...
