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Sustained elevation of extracellular ATP in chronic glaucoma

Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...

What’s next in retinal imaging? Faster, deeper and full-on

Fast-evolving technological leaps are opening the way toward clinically useful ocular coherence angiography, generating 3-dimensional microvasculature maps without intravenous dye injection, as well as whole-eye imaging, handheld patient-operated optical coherence tomography (OCT) devices and, for challenging vitreoretinal procedures, integrated intraoperative...

In conversation with Captain Gary Dyson

Captain Gary Dyson, Chief Pilot of the Orbis Flying Eye Hospital, spoke to Chris Henson about his 22-year stint flying the plane, its role at the cutting edge of aviation and medical technology, and how Orbis plan to continue to...

White dot syndromes

It is fair to say that trainees and consultants who are not medical retina specialists are a bit scared of the so called retinal ‘white dot syndromes’. It is easy to understand why this is the case, as almost every...

The gift of family

“Your kids look just like you!” is an oft-heard phrase at family gatherings. Setting aside the obvious explanation of basic genetics, similarities and recurrent character traits are well recognised within a family unit. Shared positive mutual experiences shape these attitudes...

Community Eyecare Services in Northern Ireland: putting the patient at the centre, improving outcomes and maximising system resource

The UK has four healthcare systems; Northern Ireland, Scotland and Wales each has autonomous legislature that develops health policy, while the UK government directly runs England’s NHS. Like the other nations, Northern Ireland is continually challenged to meet the needs...

Keratoconus: When, Why and Why Not. A Step by Step Systematic Approach

This is a single author publication addressing the subject of ectatic corneal disorders and keratoconus (when, why, and why not) with a step by step systematic approach to management using modern sophisticated diagnostic and screening tools. It is comprised of...

A Case-Based Guide to Eye Pain: Perspectives from Ophthalmology and Neurology

A refreshing, systematic approach to eye pain, arguably one of the most commonly presenting symptoms and one that can be fraught with diagnostic challenges and management dilemmas for the busy clinician. There is a scarcity of books covering this particular...

Ophthalmology Lecture Notes (Twelfth Edition)

During medical school, our seniors often told us that the easiest way to remember something is to understand it. And rightly so, when I came across the Ophthalmology Lecture Notes textbook as a student I realised that the key to...

Are corneal guttata an additional risk factor in complicated cataract surgery needing a future corneal transplant?

This registry-based cohort study from Sweden utilised data from the Swedish National Cataract Registry and the Swedish Cornea Transplant Registry. Patients who underwent phacoemulsification with a posterior intraocular lens between 2010 and 2012 numbered 192,476. Of these cases, 288 underwent...

Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

How reliable is the postoperative diplopia test and can it predict postoperative outcomes?

A two-phase process evaluating the postoperative diplopia test is presented. A standardised operating procedure was used for conducting all postoperative diplopia tests for this study which is described in the paper. Phase one focused on reliability, test-retest and interobserver. Adults...