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Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

More sensitive visual acuity test for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

Sight loss experts warn Edinburgh eye health being neglected

Sight Scotland and Sight Scotland Veterans launch petition calling for new eye hospital in the capital.

Orbis named winner of 2023 Amazon Web Services IMAGINE grant for non-profits

Orbis will work with Amazon's cloud computing arm to expand access to artificial intelligence-assisted eye screenings in Asia and Africa.

Orbis Brings Sight-Saving Glaucoma Training to Rural Peru

International eyecare charity Orbis has kicked off a five-day, on-site hospital training programme in Trujillo, Peru, to enhance the skills of local eyecare professionals in treating glaucoma.

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Evaluation of fluocinolone acetonide in the management of BRC

This is a single-centre, retrospective, intervention study of 15 eyes of birdshot retinochoroiditis (BRC) patients who received Iluvein, with a mean follow-up period of 31 months. Five eyes had previously received dexamethasone intravitreal implant 0.7mg (Ozurdex). Fluorescein angiography (FA) showed...

Reduction of severe visual loss and complications following IAC for RB

This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...

Ophthalmology practice during COVID-19

The purpose of this study was to share the experiences in treating paediatric ophthalmology patients during the pandemic and to report institution guidelines. A flowchart was devised for telephone triage and subsequent follow-up of patients through telemedicine or face to...

Refractive changes over time for fully accom esotropia

The purpose of this study was to determine refractive error changes across time and to define factors contributing to decompensation in patients with fully accomodative esotropia (FAET). This was a retrospective study of 223 patients with a mean age at...

Glaucoma surgery in Sturge-Weber syndrome

The authors report the largest retrospective study of surgical results of goniotomoy and trabeculectomy for 42 patients (46 eyes) with glaucoma associated with Sturge-Weber syndrome (SWS). There were 18 males and 24 females, and 62 goniotomy procedures (51 goniotomy surgery,...

Sebaceous gland carcinoma

This is a review of 241 patients diagnosed with periocular sebaceous gland carcinoma which investigates whether age at presentation influences either the clinical presentation or the outcomes of treatment. Twelve percent of patients were classified as young (<40 years old),...