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Differential diagnosis of retinoblastoma and pseudo retinoblastoma

The authors reviewed the rate of pseudo retinoblastoma (PRB) among cases referred for suspicion of RB at a tertiary referral centre in Turkey and the distribution of PRB cases according to age. This was a retrospective study of 549 patients...

ICG TTT for retinoblastoma

Transpupillary thermotherapy (TTT) is a specific form of ocular TT using infrared radiation (diode laser). Indocyanine green (ICG) is also used to achieve the optimal phototherapy effect in eyes with minimal pigment. Twenty-one patients with 42 retinoblastomas in 30 eyes...

Retinoblastoma in older children

Retinoblastoma is the most common ophthalmic malignancy in childhood and over 90% are diagnosed before the age of five years. It is not often suspected in older children given its rarity and unusual clinical findings which complicates the diagnosis. The...

Melphalon treatment of retinoblastoma

The purpose of this study was to report the authors’ experience with superselective ophthalmic artery infusion of Melphalon (SOAIM) for the treatment of five cases of unilateral sporadic retinoblastoma involving the macula. Standard therapy included a cycle of three infusions...

Results of changed treatment for retinoblastoma

Systemic chemotherapy was adopted in Kobe in 1996. In this study the authors analyse the clinical manifestations and results of treatment for patients with retinoblastoma since then. This review is of 43 eyes of 34 patients. Those with follow-up to...

Enucleation refusal for retinoblastoma

Retinoblastoma is the most common eye cancer in childhood, with enucleation rarely being the only lifesaving surgical option, especially where evidence of extraocular spread is apparent. This study sought to survey a global pool of eye care professionals with regards...

OCT use with macular retinoblastoma

The authors explore the use of portable hand-held spectral domain OCT (SD-OCT) in three eyes of three infants and young children with macular retinoblastoma. All were treated with chemotherapy and all had SD-OCT before and after treatment. The children were...

Delayed EPBRT efficacy in retinoblastoma

This is a retrospective medical records review of 50 patients (54 eyes) with retinoblastoma (RB), who received I-125 episcleral plaque brachytherapy (EPBRT) prior to (primary) or following chemoreduction (delayed) alone and in combination with non-irradiative focal therapy. Fifty-six plaques were...

Online retinoblastoma surveillance tool

Given the vision and life-threatening course of retinoblastoma (RB), it has become a significant heritable childhood cancer to screen for. To recommend surveillance, risk must be estimated and genetic testing plays a vital role. However, genetic tests vary based on...

Presenting and diagnostic signs of retinoblastoma

This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...

Outcomes of plaque radiotherapy for retinoblastoma

The study authors evaluate their experience of plaque radiotherapy for retinoblastoma (RB) in 41 eyes of 41 patients that failed intra-arterial chemotherapy (IAC). This was a retrospective review including 21 females and 20 males. Median age was 18 months and...