You searched for "anti-VEGF"
Atrophy and anti-VEGF
1 August 2019
| Saruban Pasu
|
Retina / Uvea / Vitreous
The aim of this study was to investigate treatment factors, along with ocular and systemic factors for their association with macular atrophy (MA) incidence in eyes with neovascular age-related macular degeneration (nAMD) treated with anti-VEGF aflibercept or ranibizumab according to...
Progression of macular atrophy on long-term anti-VEGF therapy for AMD
3 October 2022
| Sofia Rokerya
|
Retina / Uvea / Vitreous
|
Anti-VEGF therapy, Long term, Macular atrophy, neovascular age-related macular degeneration
This retrospective study evaluated the progression of macular atrophy in 53 eyes of 53 patients receiving AntiVEGF Therapy for age-related macular degeneration (nAMD), for at least six years. None of the patients had any macular atrophy (MA) at presentation. MA...
ROP anti-VEGF treatment review
3 June 2021
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
The purpose of this review was to consider data relating to risks and benefits of the use of anti-VEGF treatment for retinopathy of prematurity (ROP) over the past five years of 2015-2020. Ocular benefits include treatment of aggressive posterior ROP,...
Type 3 CNV and anti-VEGF
1 February 2019
| Saruban Pasu
|
Retina / Uvea / Vitreous
The purpose of the study was to determine the differences between aflibercept and ranibizumab in terms of their therapeutic efficacy in the treatment of Type 3 neovascularisation. The authors highlight that the dominant mechanism for Type 3 neovascularisation development is...
Systemic pharmacology of intravitreal anti-VEGF
1 April 2018
| Saruban Pasu
|
Retina / Uvea / Vitreous
This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...
The effects of anti-VEGF therapy for NvAMD on retinal vasculature
4 August 2021
| Su Young
|
Retina / Uvea / Vitreous
|
aflibercept, foveal avascular zone, neovascular age-related macular degeneration, ranibizumab, retinal vessel density
This retrospective consecutive case series examined 54 eyes of 54 treatment-naïve neovascular age-related macular degeneration (N-AMD) patients. Thirty-three eyes received intravitreal aflibercept injections, and 21 eyes received intravitreal ranibizumab injections with unaffected fellow eyes (54 eyes) as controls. All image...
Effect of anti-VEGF treatment on PED morphology
1 June 2015
| Jaya Myneni
|
Retina / Uvea / Vitreous
|
Choroidal neovascularization, optical coherence tomography, ranibizumab, VEGF
This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...
Combined anti-VEGF and PDT for wet AMD
1 February 2014
| Brian Ang
|
Retina / Uvea / Vitreous
The authors report on a retrospective case series of combined anti-VEGF and photodynamic therapy (PDT) in the treatment of wet age-related macular degeneration (AMD) refractory to anti-VEGF monotherapy alone. The criteria for treatment failure of anti-VEGF monotherapy were persistent subretinal...
Endophthalmitis after intravitreal anti-VEGF injection
1 August 2019
| Sofia Rokerya
|
Retina / Uvea / Vitreous
|
Endophthalmitis, Intravitreal injection, Vascular endothelial growth factor
The authors report the results of a retrospective multicentre study conducted at 17 retina referral centres to investigate the microbial spectrum of endophthalmitis after anti-VEGF injections. A total of 83 cases of culture-positive endophthalmitis (58.4%) were included. The most frequent...
Evaluation of Optive® in ocular discomfort after anti-VEGF intravitreal injection
1 October 2021
| Sofia Rokerya
|
Retina / Uvea / Vitreous
|
Artificial tear, Intravitreal injection therapy, Ocular discomfort, Ocular surface
In this study the authors prospectively evaluated the efficacy of Optive® eye drops after in full, then abbreviation - intravitreal injection (IVT). Patients naïve to IVT were included in the study. No artificial tear treatment was prescribed after the first...
OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema
1 December 2021
| Su Young
|
Retina / Uvea / Vitreous
|
Diabetic macular edema, aflibercept, optical coherence tomography, predictive, ranibizumab
This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....
21st Century retinal laser treatment in the anti-VEGF era
1 June 2017
| John Awad, Prasad Rao
|
Retina / Uvea / Vitreous
In today’s world, macular laser treatment has a vital role in the treatment of diabetic macular oedema (DMO). DMO is one of the most common causes of visual impairment. Despite expensive intravitreal treatment courses of anti-VEGF, many will agree that...