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Embryology in clinical practice

1 February 2016 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
The fascinating world of embryology is both beautiful and practical. It is a home video of our evolutionary history through the ages from the single cell through to the life aquatic, the development of gut, limbs and brain, and most...

Corneal Topography in Clinical Practice (Pentacam System)

1 February 2014 | | Imaging, Cornea / External Eye Disease, Ophthalmology
This book is based upon one device, the Pentacam, developed by OCULUS, and is primarily aimed at those who wish to familiarise themselves with the Pentacam system and need a text to complement the instrument operations manual. It is laid...

The refractive index in the eye lens – implications for clinical practice and optical design

1 August 2016 | | Cataract and Refractive
The eye may appear to be a comparatively simple organ and yet its optical system is complex and continues to be a source of investigation and research. The major optical elements are considered to be the cornea and the lens...

Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

5 June 2023 | | Neuro-Ophthalmology | AQP4, MOG, MOGAD, Multiple sclerosis, NMOSD, optical coherence tomography
Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

PRN Ranibizumab verses continuous aflibercept in UK clinical practice

1 October 2018 | | Retina / Uvea / Vitreous | Age related macular degeneration, aflibercept, anti-VEGF therapy, ranibizumab
This was a multicentre (21 UK hospitals), national EMR study on treatment naïve nAMD eyes, undergoing predominantly as needed (PRN) Ranibizumab or continuous (fixed or treat and extend - (F/TE)) Aflibercept (Af). The primary outcome was change in vision at...

Treatment for post stroke visual impairment – clinical practice versus literature evidence

1 April 2018 | | Neuro-Ophthalmology | Management, stroke, treatment, vision, visual impairment
The aim of this paper is to compare the treatments reported in a large scale stroke study (Vision in stroke (VIS) Study) against the treatments identified in a full systematic literature review. The purpose was to identify which treatment /...

Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice

1 February 2015 | | Retina / Uvea / Vitreous
The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...

Children with ‘lazy eye’ are at increased risk of serious disease in adulthood

11 March 2024 | education, research, oculomics, amblyopia, biomarkers, Siegfried Wagner, UCL
Adults who had amblyopia (‘lazy eye’) in childhood are more likely to experience hypertension, obesity, and metabolic syndrome in adulthood, as well as an increased risk of heart attack, finds a new study led by UCL researchers.

A window to 2024 and beyond?

3 April 2024 | | Ophthalmology
The connection between the eye and systemic diseases has been acknowledged for millenia. Historical records suggest that ancient civilisations had some understanding of the eye’s significance beyond its primary function in vision. For instance, in ancient Egypt, the ‘Eye of...

The ocular manifestations of COVID-19: an overview of current literature

6 April 2021 | | Ophthalmology, Cornea / External Eye Disease, Retina / Uvea / Vitreous, Neuro-Ophthalmology, COVID-19
Although respiratory symptoms are the most frequent manifestation of COVID-19, multi-organ involvement has been demonstrated, including ocular manifestations. The author investigates how the eye can be affected. The SARS-CoV-2 virus responsible for the COVID-19 pandemic has presented a significant public...

The Lancet Global Health Commission on Global Eye Health: vision beyond 2020

2 August 2022 | | Ophthalmology
Introduction The Lancet Global Health Commission on Global Eye Health was published in 2021 [1]. Drawing on expertise from within and outside the eye health sector, the Commission set out to: inform governments and other stakeholders about the path forward...