You searched for "cyclosporine"
Cyclosporine A and pterygium fibroblasts
1 October 2015
| Magdalena Popiela
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Cornea / External Eye Disease
The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...
Topical cyclosporine A 0.05% for recurrent anterior uveitis
1 August 2016
| Jonathan Chan
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Retina / Uvea / Vitreous
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Immunology, Inflammation, Treatment Medical
This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...
New Treatments in Noninfectious Uveitis
As a specialist registrar training in Aberdeen there were two important lessons I learned which have proved to be invaluable over the years for two very different reasons. The first lesson learned was to never underestimate the wind chill factor...Emerging developments in dry eye
1 August 2017
| Rod McNeil
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EYE - Cornea
An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...
Birdshot chorioretinopathy: an important differential
1 April 2015
| Zaria Ali, Mohammed Alarbi, Salwa Abugreen
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AMD, Emergency Ophthalmology, Genetics, Ophthalmology, Optometry, EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Birdshot chorioretinopathy (BSCR) is a relatively uncommon cause of posterior uveitis which often has a relapsing and remitting course [1,2]. We present a case which demonstrates how remission can be obtained for several years using cyclosporine. Case report A 44-year-old...
Management of ocular surface disease
3 February 2023
| Jonathan Chan
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Cornea / External Eye Disease
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conjunctiva, cornea, drugs, inflammation
This is a retrospective study of patients with ocular surface disease (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease), active...
VKH outcomes with pulse IV steroids
1 April 2019
| Jonathan Chan
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Retina / Uvea / Vitreous
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Vogt-Koyanagi-Harada disease, corticosteroids, cyclosporine, treatment, visual outcome
This is a retrospective review of clinical case notes records of 111 Vogt-Koyanagi-Harada (VKH) patients between 1999 and 2015 from a single centre in Tokyo, Japan. The mean age at presentation was 41 years and the median follow-up period was...
Cataract surgery in patients with Vogt-Koyanagi-Harada
1 February 2019
| Tasmin Berman
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Retina / Uvea / Vitreous
This retrospective, interventional case series of 286 patients (408 eyes) assessed visual outcome and prognostic factors in patients with Vogt-Koyanagi-Harada (VKH) undergoing cataract surgery between September 2008 and December 2017. Two groups were reviewed. The first group (352 eyes) had...
Inflammatory macular holes
1 April 2014
| Saruban Pasu
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Ophthalmology
The authors present a case of closure of a full thickness macular hole in a patient with Behçet’s disease, without surgery. The 23-year-old male they describe presented with a history of recurrent oral aphthous ulcers and a genital ulcer. Ocular...
The use of adalimumab for relapse in patients with Vogt-Koyanagi-Harada disease
2 August 2024
| Zina Mobarak
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Retina / Uvea / Vitreous
In this retrospective, multi-centre, cohort study, the efficacy and safety of Adalimumab (ADA) treatment for the exacerbation or recurrence of Vogt-Koyanagi-Harada (VKH) patients was assessed by investigating the medical records of patients who had received ADA treatment for more than...
Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases
3 April 2023
| Kurt Spiteri Cornish
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Cornea / External Eye Disease
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conjunctiva, cornea, drugs, inflammation
This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...
PUK after corneal crosslinking
1 April 2019
| Bushra Thajudeen
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Cornea / External Eye Disease
This retrospective study aimed to report the incidence, characteristics, clinical presentations, risk factors, and the available treatment modalities of sterile peripheral ulcerative keratitis (PUK) post-corneal collagen crosslinking (CXL). In total 771 eyes of 474 patients operated for keratoconus or ectasia...