You searched for "diabetic retinopathy"
Management of proliferative diabetic retinopathy
1 August 2014
| Felicity Allen, Samantha S Mann
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Retina / Uvea / Vitreous
Diabetic retinopathy is a major cause of blindness in the working-age population. Due to the worsening global epidemic of diabetes, the incidence of morbidity caused by the disease is set to increase [1]. The prevalence of diabetes in the UK...
OCT in proliferative diabetic retinopathy
1 December 2017
| Saruban Pasu
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Retina / Uvea / Vitreous
This report set out to describe the anatomical relationships between retinal neovascular complexes (NVC), the posterior vitreous, and the vitreoretinal interface in patients with proliferative diabetic retinopathy using spectral domain OCT. The following was recorded for each NVC 1) posterior...
A possible biomarker for diabetic retinopathy
1 August 2017
| Graham Wallace
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Retina / Uvea / Vitreous
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Alternative splicing, Delta-1, Diabetic retinopathy, RNA expression, Tubulin, Whole transcriptome analysis
Diabetic retinopathy (DR) is the most common form of diabetic eye disease, characterised by exudates, microaneurysms and haemorrhage. Early diagnosis is crucial for preventing visual loss. The risk of developing diabetic retinopathy is known to increase with age as well...
Inflammation and microvascular changes in diabetic retinopathy
1 February 2022
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
Effect of heredity on risk of diabetic retinopathy
1 September 2023
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Diabetic macular edema, heredity, proliferative diabetic retinopathy, risk factors, survival analysis
This study used survival analysis on 2199 patients who had reached vision-threatening diabetic retinopathy to investigate the contribution of heredity to diabetes together with other known risk factors for the development of either proliferative diabetic retinopathy (PDR) or diabetic macular...
Automated grading of diabetic retinopathy: is it possible?
1 August 2018
| Eulee Seow
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Retina / Uvea / Vitreous
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automated, diabetic retinopathy, pseudocolour, ultrawidefield
Diabetic retinopathy (DR) is a frequent microvascular complication of diabetes and a leading cause of blindness worldwide. However, much of this diabetic blindness can be delayed or even prevented with timely diagnosis and proper treatment. For this reason, regular screening...
Myopia-protective against diabetic retinopathy
1 October 2016
| Bheemanagouda Patil
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Retina / Uvea / Vitreous
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axial length, diabetic retinopathy, meta-analysis, myopia
This meta-analysis evaluates the current evidence of the relationship between myopia and diabetic retinopathy (DR) risk. A systematic search was performed up to April 2015. Three models were used to assess the association between myopia and risk of DR: axial...
Medical management and diabetic retinopathy progression
1 February 2015
| Brian Ang
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Retina / Uvea / Vitreous
The ACCORD Eye Study was designed to evaluate the benefit of intensive glycaemic control (HbA1c <6.0% vs 7.0-7.9%), intensive systolic blood pressure control (<120mmHg vs. <140mmHg), and combined fenofibrate and simvastatin therapy in the development and progression of diabetic retinopathy....
Is myopia protective against progression of diabetic retinopathy?
2 December 2019
| Tasmin Berman
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Retina / Uvea / Vitreous
This population-based cohort study assessed the association of refractive error with the incidence and progression of diabetic retinopathy (DR); 1562 eyes of 860 patients with diabetes and gradable retinal photographs were included. Baseline data was taken between 2004-2009 and follow-up...
Retinal ischaemia on OCTA and diabetic retinopathy grade
1 April 2020
| Saruban Pasu
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Retina / Uvea / Vitreous
The authors quite rightly point out that quantification of retinal ischaemia has the potential to serve as a biomarker for diabetic retinopathy disease progression. They set out to investigate the relationship between area of ischaemia on a swept source OCTA...
ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy
1 June 2018
| Graham Wallace
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Retina / Uvea / Vitreous
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Adipocytokine, Angiopoietin-like protein-4 (ANGPTL-4), Diabetic retinopathy (DR), Hypoxia inducible factor-1 alpha (HIF-1α), Inflammation, Profilin-1
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Retinal ganglion cell loss in diabetes and diabetic retinopathy
1 October 2016
| Anjali Gupta
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Retina / Uvea / Vitreous
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diabetes, diabetic retinopathy, neuronal damage, optical coherence tomography, retinal ganglion cell
The aim of this observational case control study was to evaluate the association of diabetes and diabetic retinopathy (DR) with retinal ganglion cell loss. Cases were Chinese patients with type 2 diabetes with and without DR, aged 40-80 years. Eligible...