You searched for "fibre layer"
Retinal nerve fibre layer thickness in migraine
2 February 2024
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
The aim of this study is to evaluate retinal nerve fibre layer (RNFL) thickness changes in children with migraine compared to healthy controls and analyse RNFL changes dependent on type of migraine. This was an observation case control study of...
Density of cataract and its influence on retinal nerve fibre layer thickness
1 December 2013
| Nana Theodorou
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Retina / Uvea / Vitreous
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cataract, image quality, optical coherence tomography, retinal nerve fibre layer
The aim of this study was to further define and model the influence of cataract on spectral domain optical coherence tomography (SDOCT) image quality and retinal nerve fibre layer (RNFL) thickness measurements. OCT quality is influenced by opacities in the...
Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Optic neuritis, axonal degeneration, neurofilament protein, retina, tissue
Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...
Investigating the effect of signal strength on mean retinal nerve fibre layer
7 December 2020
| Claire Howard
|
EYE - Neuro-ophthalmology
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OCT, RNFL, Retinal nerve fiber layer, Spectralis, optical coherence tomography, signal strength
The aim of this study was to determine the effect of signal strength on mean retinal nerve fibre layer (RNFL) using spectralis optical coherence tomography (S-OCT). Thirty normal subjects were imaged with S-OCT using variably dense Bangerter foils to alter...
Effect of change in retinal nerve fibre layer thickness on quality of life in patients with glaucoma
1 October 2015
| Lona Jawaheer
|
EYE - Glaucoma
The authors investigated the relationship between structural changes in glaucoma (retinal nerve fibre layer (RNFL) thickness) and quality of life (as measured by the NEI VFQ-25 questionnaire) over a period of time. Two hundred and sixty eyes of 130 patients...
Mast cells in Graves’ ophthalmopathy
1 August 2016
| Bheemanagouda Patil
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Ophthalmology
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Graves’ ophthalmopathy, Histamine, Histamine receptor type-1, Loratadine, Mast cell, NF-κB controlled cytokine, NF-κB inhibitor, Orbital fibroblast
Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...
Cyclosporine A and pterygium fibroblasts
The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...Jun/Jul 2015 Quiz
1 June 2015
| Hardeep Singh Mudhar
|
EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 35-year-old male presents with bilateral corneal opacities. Examination shows a honeycomb-type dystrophy. A penetrating keratoplasty is performed and the specimen sent for ophthalmic histopathological assessment. Figure 1 is the haemotoxylin & eosin (H&E). Figure 2 is a Masson...
Bioengineered human tissue
1 August 2017
| James Hsuan
|
EYE - Pathology, EYE - Oncology
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ocular, oculoplastic, reconstructive, bioengineering, reconstruction, oculoplastics, orbit
This is a literature review of the current status of tissue engineering related to ocular and oculoplastic reconstructive surgery. The authors describe the process of bioengineering for tissue reconstruction. The aim is to reproduce functional tissue by the use of...
Stromal cell alignment in damaged cornea
1 August 2017
| Graham Wallace
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EYE - Cornea, EYE - General
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Confocal microscopy, Corneal wound healing, Extracellular matrix, SHG imaging
Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...
Money never sleeps
“I want you to deal with your problems by becoming rich” As declared by Jordan Belfort in a motivational speech to his staff in the film Wolf of Wall Street (2013). Unfortunately, medicine as a career does not lead to...
HtrA1 enhances cell senescence
1 December 2013
| Graham Wallace
|
Retina / Uvea / Vitreous
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
