You searched for "inflammatory"
Inflammatory macular holes
1 April 2014
| Saruban Pasu
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Ophthalmology
The authors present a case of closure of a full thickness macular hole in a patient with Behçet’s disease, without surgery. The 23-year-old male they describe presented with a history of recurrent oral aphthous ulcers and a genital ulcer. Ocular...
The inflammatory side-effect of Brimonidine
1 October 2016
| Saruban Pasu
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Retina / Uvea / Vitreous
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Brimonidine uveitis, drug induced uveitis
Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...
Differential diagnosis of inflammatory optic neuritis
1 February 2014
| Claire Howard
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Neuro-Ophthalmology
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Multiple sclerosis, neuromyelitis optica, optic neuritis
The authors present the differential diagnosis of inflammatory optic neuritis (ON) to include multiple sclerosis, infectious optic neuritis, systemic disease and neuromyelitis optica (NMO). The features of ON for the varying aetiologies are detailed including incidence and overlap. In acute...
Serology testing in periocular inflammatory disease
1 December 2016
| James Hsuan
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Ocular Pathology and Oncology
This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....
Distribution, progression, and outcomes of inflammatory chorioretinal lesions
1 December 2022
| Kelvin Cheng
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Retina / Uvea / Vitreous
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Autofluorescence, inflammatory lesions, multifocal choroiditis, multimodal imaging, optical coherence tomography, punctate inner choroidopathy, uveitis
This study investigated the distribution and progression of multifocal choroiditis (MFC) inflammatory lesions in 25 eyes of 20 patients and their correlations with clinical outcomes at 24 months. The distribution of choroiditis inflammatory lesions were evaluated semi-automatically using a dedicated...
AMD and visceral fat and pro-inflammatory factors
1 December 2015
| Bheemanagouda Patil
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Retina / Uvea / Vitreous
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AMD, body mass index, pro-inflammatory factors, visceral fat
Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...
Choroidal changes in multisystem inflammatory syndrome in children
This study aimed to evaluate the vascular structure of the choroid in multisystem inflammatory syndrome in children (MIS-C). This was a prospective study of 38 eyes of 19 patients and 60 eyes of 30 healthy controls. None had ocular pathology....Insects, swelling and sight loss: a case of orbital inflammatory syndrome
1 June 2022
| Parushak Rezai, Susan Sarangapani
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Ophthalmology
Despite being the most common cause of painful orbital mass in adults and the third most common orbital disease, orbital inflammatory syndrome still proves to be a difficult ocular condition to diagnose, treat, and manage. A 41-year-old lady presented to...
Idiopathic orbital pseudotumor as first sign of systemic inflammatory disease
4 February 2021
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
The authors describe four children in whom idiopathic orbital pseudotumor (IOP) was the initial solitary finding with systemic inflammatory disease developing later. Four children were seen over a five-year period. Mean age was 9.75 years (2-14). Three were white and...
Systemic anti-inflammatory versus fluocinolone acetonide intraocular implant
1 February 2016
| Brian Ang
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Ophthalmology
In the Multicenter Uveitis Steroid Treatment (MUST) trial, 255 patients with intermediate uveitis, posterior uveitis or panuveitis were randomised to either fluocinolone acetonide intraocular implant or systemic corticosteroid therapy which was supplemented with immunosuppression if required. Patients were followed up...
Topical nonsteroidal ant-inflammatory drugs (NSAIDs) in patients undergoing cataract surgery
4 February 2021
| Kurt Spiteri Cornish
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Cataract and Refractive
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Postoperative inflammation, cataract surgery, diclofenac, laser flare meter, nepafenac
Inflammation is a major risk factor for the development of cystoid macular oedema (CMO) after cataract surgery, leading to breakdown of the blood-retina barrier. There is a correlation between severity of CMO and level of postoperative inflammation. Laser flare meter...
Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases
3 April 2023
| Kurt Spiteri Cornish
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Cornea / External Eye Disease
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conjunctiva, cornea, drugs, inflammation
This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...