You searched for "limbal"
Complications of limbal stay sutures
3 October 2022
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
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Stay sutures, complications, strabismus surgery
There is limited literature describing complications at the limbal suture site. The authors describe two cases with postoperative complications due to use of intraoperative limbal stay sutures. Each case had strabismus surgery at other centres but with presentation to the...
Limbal melanocytes and the stem cell niche
1 February 2016
| Graham Wallace
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Retina / Uvea / Vitreous
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Cell interactions, Cornea, Limbal stem cells, Melanocytes, Stem cell niche
The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...
Allografts in limbal stem cell deficiency
1 August 2015
| Saruban Pasu
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EYE - Cornea, EYE - General
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Cadaveric keratolimbal allograft, limbal stem cell deficiency, limbal stem cell transplantation, live related allograft
This prospective comparative study compared outcomes of live related limbal allograft (Lr-CLAL) versus cadaveric keratolimbal allograft (KLAL) in limbal stem cell deficiency secondary to ocular burns. Twenty patients were randomly allocated into each group. The Lr-CLAL group had a significant...
Characteristics of limbal lymphatic vasculature on confocal microscopy
This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...
Outcomes after surgical excision of limbal dermoid
5 April 2022
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
The authors aimed to report the visual and refractive outcomes and complications of simple excision of limbal dermoid (LD) sparing the visual axis and Descemet’s membrane in children aged ≤8 years. This was a retrospective review over 2000-2019 including 19...
Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants
1 October 2014
| Aws Al-Hity, Sanjay Mantry, Ken Lai, K Ramaesh
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EYE - Cornea
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...
Boston type I keratoprosthesis for limbal stem cell deficiency
Boston type I keratoprosthesis (KPro) long-term outcomes were compared in patients with and without limbal stem cell deficiency (LSCD) in this retrospective study. In the 11 year period 68 procedures were performed in individuals with LSCD, and 105 procedures in...Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency
An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...
Ocular surface in donor eyes after CLAU
This retrospective study examined ocular surface stability of donor eyes following conjunctival limbal autografts (CLAU). Forty-five eyes underwent CLAU with chemical burns being the most common indication. All but two eyes had just over 4 o’clock hours of CLAU segment...
Rectus muscle insertion shift at surgery
1 October 2021
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
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Limbal-insertion distance, insertion shift, rectus muscle insertion
The authors conducted this study to evaluate the shift in rectus muscle insertion when the muscle is disinserted from the globe but before it is recessed and / or transposed. They measured the amount of central rectus muscle insertion shift...
Stem cell transplantation and pterygium surgery
28 November 2022
| Aina Pons, Abhinav Loomba
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EYE - General
Pterygium is a benign, fibrovascular overgrowth of bulbar conjunctiva extending onto the cornea and has been associated with ultraviolet (UV) light exposure. The prevalence of pterygium worldwide varies between geographical zones but has been reported to range between three and...
Resurfacing the ocular surface
1 April 2016
| Harminder Dua (Prof)
|
EYE - Cornea
The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...
