Journal Reviews
Oral azithromycin for meibomian gland disease
Oral tetracyclines have been the traditional systemic treatment of blepharitis and acne rosacea, through inhibiting bacterial lipase production and reducing fatty acids. However, tetracyclines have a number of adverse side-effects and are required to be taken for a long duration...
C-spp corneal consequences
This is a retrospective review of microbiological records of 22 patients, who had presented at the LV Prasad Eye Institute, India, between June 2009 and December 2012. The corneal scrapings were performed in all patients and had yielded significant growth...
Boston type I keratoprosthesis for limbal stem cell deficiency
Boston type I keratoprosthesis (KPro) long-term outcomes were compared in patients with and without limbal stem cell deficiency (LSCD) in this retrospective study. In the 11 year period 68 procedures were performed in individuals with LSCD, and 105 procedures in...
Bitemporal hemianopsia as a result of ethambutol toxicity
The authors present six cases of visual loss in patients treated with ethambutol for mycobacterium avium complex, including four patients with bitemporal hemianopsia. Two additional patients were undergoing glaucoma monitoring and developed visual field defects with ethambutol treatment, which recovered...
Case report of Leber hereditary optic neuropathy (LHON)
This case report presents a 74-year-old male patient who developed LHON, with a previous diagnosis of bilateral macular holes. LHON occurs predominantly in healthy young men and onset in older age ranges increases the likelihood that the patient will have...
Review of non-arteritic anterior ischaemic optic neuropathy
This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...
Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...
PlusoptiX and SPOT screening
The goal of this study was to determine whether an instrument that uses referral criteria having a high specificity (plusoptiX S08) would fail to refer children who have significant amblyopia and who would have been detected by an instrument using...
Carbonic anhydrase II autoantibody specificity in retinopathy
Autoimmune retinopathy (AR) can be divided into three different categories, paraneoplastic retinopathy, including recoverin-associated retinopathy and melanoma-associated retinopathy, non-paraneoplastic autoimmune retinopathy, combined paraneoplastic optic neuropathy and retinopathy (CAR). These conditions are characterised by circulating anti-retinal autoantibodies, possibly due to a...
Enucleation refusal for retinoblastoma
Retinoblastoma is the most common eye cancer in childhood, with enucleation rarely being the only lifesaving surgical option, especially where evidence of extraocular spread is apparent. This study sought to survey a global pool of eye care professionals with regards...
Dog bite lid lacerations
The characteristics of dog bite induced lid trauma are described in a large cohort of paediatric patients and the success rate of early repair of lacerations involving the lacrimal system. This is a retrospective review of 438 patients: 73 with...
Long-term esotropia and exotropia alignment
The authors review surgical outcomes for 317 children having surgery for esotropia (n=235) or exotropia (n=82) for comparative analysis using survival curves. Esotropia surgery was undertaken at a mean of 42 months; exotropia surgery at a mean of 60 months...
