Long-term outcomes of intravitreal ranibizumab for neovascular AMD

This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...

Topical cyclosporine A 0.05% for recurrent anterior uveitis

This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...

Intravitreal afibercept and ranibizumab for PCV

This is a retrospective, interventional series comprising 98 eyes with polypidal choroidal vasculopathy (PCV) with the aim of comparing treatments with afibercept and ranibizumab, highlighting any differences in their efficacy. Case notes and imaging (FFA / ICG / OCT) were...

Screening for hydroxychloroquine retinopathy

The American Academy of Ophthalmology has updated the recommendations for screening for hydroxychloroquine retinopathy based on new scientific evidence that toxicity is not rare when hydroxychloroquine is used long-term, and that risk is dependent on the daily dose by weight....

Aflibercept, bevacizumab or ranibizumab for DMO

This is a two-year randomised clinical trial of 660 patients with visual acuity impairment from diabetic macular oedema (DMO) who were randomised to monthly injections of 2.0mg aflibercept, 1.25 mg bevacizumab or 0.3mg ranibizumab. Focal or grid laser was performed...

Hereditary profile of retinal detachment

This review sought to clarify some of the heritable elements of rhegmatogenous retinal detachment (RRD). The familial element of RRD is well established, with the sibling recurrence risk ratio being 2.1 (Mitry and colleagues), and the parent-offspring recurrence risk ratio...

Lacrimal gland carcinoma

This is a major review of the management of lacrimal gland carcinoma, focusing mainly on adenoid cystic carcinoma. Relevant literature published in English since 1970 was included amounting to some 40 articles after filtering. Overall mortality for all lacrimal gland...

Lateral canthal position after lateral orbitotomy

This is a retrospective photographic study of changes in the lateral canthal position following a lateral orbitotomy performed via a lateral canthotomy and cantholysis of both upper and lower limbs of the lateral canthal tendon. Reconstruction of the lateral canthus...

Intravenous paracetamol in orbital surgery

This is a large prospective study of the effect of intravenous acetaminophen (paracetamol) in orbital surgery. The study included three groups of 50 patients. One group had no i.v. paracetamol, the second 1g of i.v. paracetamol within 30 minutes of...

Sliding lower lid tarsal flap

This is a retrospective review of a lower lid reconstructive technique utilising a sliding tarsal flap. Thirty-two patients who had undergone Mohs surgery were included and each had a shallow marginal defect with at least one remaining tarsal edge having...

Smartphone ophthalmoscopy vs. slit-lamp biomicroscopy in diabetic retinopathy

In this prospective, comparative, clinical study the authors’ aim was to assess the reliability and accuracy of smartphone ophthalmoscopy as compared with standard slit-lamp biomicroscopy in the grading of diabetic retinopathy. One hundred and twenty consecutive, new, diabetic patients underwent...

Anterior capsular tears complicating phacoemulsification surgery

This is a retrospective, interventional case series, assessing the occurrence of anterior capsular tears in phacoemulsification surgery, its effect on outcomes and further complications. Despite being a well recognised complication of phacoemulsification surgery the authors felt that there is a...