Microvasculature changes of mCNV after ranibizumab treatment using OCTA

In this study the authors aim to evaluate the vascular changes of myopic choroidal neovascularisation (mCNV) after ranibizumab treatment using optical coherence tomography-angiography (OCTA). The 3×3 OCTA en face images were analysed for the absence / presence of mCNV, CNV...

Retinal vascular occlusion from gentamicin injection post-vitrectomy

The authors present two case reports for the rare, but serious, complication of retinal vascular occlusion as a presumed result of subconjunctival injection following 25-gauge vitrectomy. Risk factors for the complication include: cardiovascular disease, retrobulbar anaesthesia, high intraocular pressure (IOP)...

Longitudinal changes in axial length in high myopia

This is a prospective, longitudinal, observational single centre study between May 2011 and September 2018, to determine the changes in the axial length (AL) longitudinally in patients with high myopia without other conformational abnormalities. Patients were divided into two groups:...

Current practice and patient selection for ISBCS in the UK

This study investigated patient and operative characteristics for immediate sequential bilateral cataract surgery (ISBCS) and delayed bilateral cataract surgery (DSCS). The annual NHS spend on cataract surgery is £500 million, a figure expected to rise by 50% in the next...

Long-term outcome of scleral-sutured posterior chamber intraocular lens

This is a retrospective review of 392 consecutive cases in 349 patients who had scleral-sutured intraocular lens (IOL) due to aphakia, subluxated or luxated IOL, over a 10-year period in one centre from Barcelona. Preop and postop data were collected...

Meta-analysis of treating meibomian gland dysfunction (MGD) with topical / oral azithromycin

This study pooled the clinical outcomes of 18 high-quality studies managing MGD with azithromycin. Symptom score was the primary and clinical signs were the secondary outcome measures. Overall effectiveness of topical azithromycin (TA) and oral azithromycin (OA) was measured by...

A case study of posterior globe flattening in idiopathic intracranial hypertension

The authors present a single case of posterior globe flattening without papilloedema in idiopathic intracranial hypertension. The case was a 64-year-old woman with a one-year history of transient visual loss in her left eye only. Visual acuity was 20/20 in...

A novel way to diagnose optic neuropathies using Bruch’s membrane opening

Differential diagnosis of optic neuropathies can be challenging but is crucial for the correct management of the underlying disease and prevention of further damage. Bruch’s membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO...

Investigating the effect of signal strength on mean retinal nerve fibre layer

The aim of this study was to determine the effect of signal strength on mean retinal nerve fibre layer (RNFL) using spectralis optical coherence tomography (S-OCT). Thirty normal subjects were imaged with S-OCT using variably dense Bangerter foils to alter...

Recurrent sebaceous gland carcinoma

In this retrospective case review study, authors report their outcomes in management of recurrent sebaceous gland carcinoma (SGC) and propose a graded protocol to manage these entities. All consecutive cases of SGC from January 2004 to December 2017 at the...

Online retinoblastoma surveillance tool

Given the vision and life-threatening course of retinoblastoma (RB), it has become a significant heritable childhood cancer to screen for. To recommend surveillance, risk must be estimated and genetic testing plays a vital role. However, genetic tests vary based on...

Orbital sphenoid sinus trauma: a rare trauma case

With a high complication and mortality rate, intra-sphenoidal and transorbital trauma poses a high complication rate and remains challenging to manage. Numerous key structures run nearby such as: the optic nerve, internal carotid arteries and ophthalmic arteries. The authors present...