Journal Reviews
Effect of trabeculectomy on corneal endothelial cell loss
This is a prospective study of 117 eyes for two years after trabeculectomy, to investigate the corneal endothelial cell density (CECD) by specular microscopy prior to and after surgery on a six monthly basis. At six, 12, 18 and 24...
Effect of caffeine and low intensity endurance exercise on intraocular pressure
This placebo controlled, double blind, balanced crossover study reports in healthy individuals that 30 minutes of cycling caused a maximum of 2.7mmHg lowering of IOP. A caffeine dose of 4mg/kg 30 minutes prior to cycling negated this effect. The conclusion...
Dacryoendoscopy in congenital nasolacrimal duct obstruction
This retrospective study demonstrates the role of dacryoendoscopy to identify causes of failed lacrimal probing in congenital nasolacrimal duct obstruction (CNLDO). Dacryoendoscopy was carried out in 13 children with refractory CNLDO. The lacrimal pathway was examined from puncta to the...
Eye movements in children with strabismus +/- amblyopia
The aim of this study was to detect eye movement recording abnormalities using different paradigms in children with strabismus in the absence or presence of amblyopia and compare these findings with age-matched children without strabismus. One hundred children were recruited...
Undetected retinoblastoma management following vitrectomy
This retrospective study from a single-centre referral university hospital in Germany analysed data collected between 1991-2019 to comment on management and complications of undetected retinoblastoma eyes following vitrectomy. The 10 patients included had a mean age of 36.1 months (range...
Evaluation of ectopia lentis et pupillae (ELP)
The ADAMTSL4 gene encodes proteins for cellular adhesion, angiogenesis, nervous system development and anterior / posterior segment structures. This case report describes a four-year-old female with diagnosis at referral of ELP. A three-generation pedigree was obtained and was negative for...
Mimicked tumour seeding due to asteroid hyalosis
A case report is presented of a patient with treated retinoblastoma (RB) who later developed asteroid hyalosis which mimicked tumour seeding. The case was a 37-year-old male with presenting symptoms of vitreous floaters. A unilateral RB was diagnosed at the...
Management of large hypertropia due to lost inferior rectus
This case report outlines the management strategy for a 37-year-old male who suffered a penetrating left orbital injury with rupture of the inferior rectus muscle, optic nerve avulsion and vertical deviation of about 90PD. On orbit exploration, the inferior rectus...
Visual acuity outcomes in Coat’s disease by classification stage
This is a retrospective study of 160 consecutive patients with Coat’s disease under the Shields classification, with Snellen visual acuity (VA) pre and post treatment. Affected eyes were categorised based on the Shields classification: Stage 1: retinal telangiectasia onlyStage 2a:...
Treat-and-extend regimen in treatment of patients with type 3 neovascularisation
Type 3 neovascularisation, also known as retinal angiomatous proliferation is a distinct subtype of neovascular AMD characterised by intraretinal neovascularisation. This retrospective study included 17 eyes diagnosed with type 3 neovascularisation who were changed from pro-re-nata (PRN) based treatment regime...
How accurate is the supplement content in both generic and branded ophthalmology supplements?
This prospective cross-section study compared the concentrations of Vitamin C, Vitamin E, Zinc, and Copper in five dietary supplements including both national and regional brands used for macular degeneration in the United States. They performed a comparative analysis using gas...
VIBIM Study: One-year results of treatment of DME with aflibercept using TnE
The VIBIM study (the treat-and-extend regimen (TER) using intravitreal aflibercept in diabetic macular edema (DME) study) was designed to evaluate the efficacy of the TER using aflibercept in the management of DME for a period of two years. The authors...
